Български
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
chronic pain/инсулт
Линкът е запазен в клипборда
Страница 1 от 53 резултата
Benzoimidazole derivatives and pharmaceutical composition comprising the same
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
TECHNICAL FIELD
The present invention relates, in general, to novel benzoimidazole derivatives and, more particularly, to novel benzoimidazole derivatives functioning as antagonists to a vanilloid receptor (capsaicin receptor; Transient Receptor Potential Channel, Vanilloid subfamily member 1;
Hydroxy-tetrahydro-naphthalenylurea derivatives
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
DETAILED DESCRIPTION OF INVENTION
Technical Field
The present invention relates to a hydroxy-tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The hydroxy-tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR1)
Cyclohexylamine derivatives as subtype selective N-Methyl-D-Aspartate antagonists
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
FIELD OF THE INVENTION
The invention provides cyclohexylamine derivatives as N-Methyl-D-Aspartate (NMDA) antagonists, pharmacological compositions comprising the derivatives, and methods of treating diseases and disorders responsive to antagonism of NMDA receptors using the derivatives.
BACKGROUND
Thiourea derivatives and the pharmaceutical compositions containing the same
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
TECHNICAL FIELD
The present invention relates to novel thiourea derivatives and the pharmaceutical compositions containing the same, and particularly, to novel thiourea compounds as a modulator for vanilloid receptor (VR) and the pharmaceutical compositions thereof. Here, the modulator means the
Tetrahydro-quinolinylurea derivatives
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
This application is a 371 of PCT/EP2004/012051, filed Oct. 26, 2004.
DETAILED DESCRIPTION OF INVENTION
1. Technical Field
The present invention relates to a tetrahydro-quinolinylurea derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-quinolinylurea
Thiourea compounds and the pharmaceutical compositions containing the same
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
TECHNICAL FIELD
The present invention relates to thiourea compounds and the pharmaceutical compositions containing the same, and particularly, to thiourea compounds with superior efficacy as an antagonist against vanilloid receptor (VR) and the pharmaceutical compositions thereof.
BACKGROUND ART
As
Substituted 2,3-benzodiazepin-4-ones and the use thereof
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
This application claims benefit of U.S. provisional application Ser. No. 60/013,813 filed Mar. 21, 1996.
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is in the field of medicinal chemistry. In particular, the invention relates to novel substituted 2,3-benzodiazepin-4-ones.
Pyrone-indole derivatives and process for their preparation
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
The alpha and gamma-pyrones are classes of compounds shown to be linked to several behavioral and pharmacological characteristics including sedative, anxiolytic, neuroprotective and antioxidative effects. Specifically, a gamma-pyrone derivative called maltol has been
4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is related to 4-substituted piperidine analogs, including hydroxypiperidine and tetrahydropyridine analogs, as well as novel intermediates of the 4-substituted analogs. The analogs are selectively active as antagonists of
2-substituted piperidine analogs and their use as subtype-selective NMDA receptor antagonists
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is related to 2-substituted piperidine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also directed to the use of 2-substituted piperidine analogs as
2-substituted piperidine analogs and their use as subtype-selective NMDA receptor antagonists
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is related to 2-substituted piperidine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also directed to the use of 2-substituted piperidine analogs as
4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is related to 4-substituted piperidine analogs, including hydroxypiperidine and tetrahydropyridine analogs. The analogs are selectively active as antagonists of N-methyl-D-aspartate (NMDA) receptor subtypes. The invention is also
Piperidine derivatives as subtype selective N-Methyl-D-Aspartate antagonists
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
FIELD OF INVENTION
The invention relates to piperidine derivatives as N-Methyl-D-Aspartate (NMDA) antagonists useful in the treatment of diseases and disorders responsive to antagonism of NMDA receptors.
BACKGROUND OF THE INVENTION
Many of the physiological and pathophysiological effects of the
Hydroxy tetrahydro-naphthalenylurea derivatives
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
TECHNICAL FIELD
The present invention relates to hydroxy-tetrahydro-naphthalenylurea derivatives which are useful as an active ingredient of pharmaceutical preparations. The hydroxy-tetrahydro-naphthalenylurea derivatives of the present invention has vanilloid receptor (VR) antagonistic activity,
Tetrahydro-naphthalene derivatives
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
DETAILED DESCRIPTION OF INVENTION
1. Technical Field
The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR) antagonistic
Най-пълната база данни за лечебни билки, подкрепена от науката
- Работи на 55 езика
- Билкови лекове, подкрепени от науката
- Разпознаване на билки по изображение
- Интерактивна GPS карта - маркирайте билките на място (очаквайте скоро)
- Прочетете научни публикации, свързани с вашето търсене
- Търсете лечебни билки по техните ефекти
- Организирайте вашите интереси и бъдете в крак с научните статии, клиничните изследвания и патентите
Въведете симптом или болест и прочетете за билките, които биха могли да помогнат, напишете билка и вижте болестите и симптомите, срещу които се използва.
* Цялата информация се базира на публикувани научни изследвания
