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Appicants have filed a number of applications concerning cough/cold formulations containing the newer non-steroidal anti-inflammatory drugs. These applications which are assigned to Richardson-Vicks, Inc. include U.S. Ser. No. 042,120, filed Apr. 24, 1987, now U.S. Pat. No. 4,783,465 which is a
Applicants have filed a number of applications concerning cough/cold formulations containing the newer non-steroidal anti-inflammatory drugs. These applications which are assigned to Richardson-Vicks, Inc. include U.S. Ser. No. 042,120, filed Apr. 24, 1987, now U.S. Pat. No. 4,783,465 which is a
BACKGROUND OF THE INVENTION
The present invention relates generally to novel pharmaceutical compositions of matter comprising one or more non-steroidal anti-inflammatory drugs (NSAID) in combination with a non-sedating antihistamine and optionally one or more other active components selected from a
BACKGROUND OF THE INVENTION
The present invention relates generally to novel pharmaceutical compositions of matter comprising one or more non-steroidal anti-inflammatory drugs (NSAID) in combination with a non-sedating antihistamine and optionally one or more other active components selected from
TECHNICAL FIELD
The present invention relates generally to a method of modulating substance P by compounds containing calcium sulfate, particularly syngenite, gorgeyite and gypsum, and more specifically, to the synthesis of such compounds as well as their use to treat a variety of conditions
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to human coronavirus 229E main proteinase (M.sup.pro) and uses in the development of inhibitors for Severe Acute Respiratory Syndrome (SARS).
2. Description of the Prior Art
Human coronaviruses (HCoV) are major causes of
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a National Stage Application under 35 U.S.C. .sctn.371 of International Application No. PCT/US2010/002360, filed Aug. 27, 2010, which claims priority under 35 U.S.C. .sctn.119(e) to U.S. Provisional Application Nos. 61/275,506, filed Aug.
FIELD OF THE INVENTION
The present invention relates to certain compounds of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB.sub.2 receptor. The present invention further relates to certain compounds of Formula Ia and pharmaceutical compositions
1. BACKGROUND OF THE INVENTION
This invention relates to novel pharmaceutical compositions containing desmethylastemizole, 6-hydroxydesmethylastemizole and norastemizole. These compositions possess potent antihistaminic activity and are useful in treating allergic rhinitis, asthma and other allergic
1. BACKGROUND OF THE INVENTION
This invention relates to novel pharmaceutical compositions containing desmethylastemizole, 6-hydroxydesmethylastemizole and norastemizole. These compositions possess potent antihistaminic activity and are useful in treating allergic rhinitis, asthma and other allergic
BACKGROUND OF THE INVENTION
This invention relates to novel pharmaceutical compositions containing 4-[1-hydroxy-4-(4-hydroxydiphenylmethyl-1-piperidinyl)butyl]-.alpha.,.alph a.-dimethylbenzeneacetates and 1-[p-(2-hydroxymethyl-2-propyl)phenyl]-4-[4-(.alpha.-hydroxy-.alpha.-pheny
BACKGROUND OF THE INVENTION
This invention relates to novel pharmaceutical compositions containing desmethylastemizole, 6-hydroxydesmethylastemizole and norastemizole. These compositions possess potent antihistaminic activity and are useful in treating allergic rhinitis, asthma and other allergic
1. BACKGROUND OF THE INVENTION
This invention relates to novel pharmaceutical compositions containing desmethylastemizole, 6-hydroxydesmethylastemizole and norastemizole. These compositions possess potent antihistaminic activity and are useful in treating allergic rhinitis, asthma and other allergic
1. BACKGROUND OF THE INVENTION
This invention relates to novel pharmaceutical compositions containing desmethylastemizole, 6-hydroxydesmethylastemizole and norastemizole. These compositions possess potent antihistaminic activity and are useful in treating allergic rhinitis, asthma and other allergic
1. BACKGROUND OF THE INVENTION
This invention relates to novel pharmaceutical compositions containing desmethylastemizole, 6-hydroxydesmethylastemizole and norastemizole. These compositions possess potent antihistaminic activity and are useful in treating allergic rhinitis, asthma and other allergic