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Effects of the naturally-occurring disaccharides, palatinose and sucrose, on incretin secretion in healthy non-obese subjects.

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OBJECTIVE Incretins might play some pathophysiological role in glucose metabolism in diabetes and obesity; it is not clear whether or not the amount and the pattern of incretin secretion vary with different types of sugars. To evaluate the effect of two types of disaccharides on glucose metabolism

Long-term efficacy and safety of acarbose in the treatment of obese subjects with non-insulin-dependent diabetes mellitus.

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BACKGROUND Acarbose delays the release of glucose from complex carbohydrates and disaccharides by inhibiting intestinal alpha-glucosidases, attenuating postprandial increments in blood glucose and insulin. This multicenter double-blind study compared the efficacy and safety of acarbose with placebo

alpha-Glucosidase inhibition in obesity.

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Acarbose is an alpha-glucosidase inhibitor which reversibly and competitively inhibits the digestion of oligo- and disaccharides at the brush border of the small intestine. This study evaluates the preventive and therapeutic properties of acarbose in the treatment of obesity. Dose-response

Long-term feeding of a synthetic diet rich in disaccharides induces hepatic fibrosis in nonalcoholic fatty liver disease in Zucker rats.

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Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease, and is commonly observed in patients with obesity or type 2 diabetes. The pathogenesis of hepatic fibrosis is clinically important to the outcome of NAFLD, however, is not well understood. Since dietary habits are often considered

[Ambulatory treatment of obesity with modified fasting (Modifast)].

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52 obese subjects, 17 to 65 years old, 42.5 +/- 23.37 percent mean body weight excess, were treated with a very low-calorie diet (1020 KJ = 240 Kcal/day), containing whole egg protein (g 33), disaccharides (g 25.5), vitamins and minerals (Modifast). The diet was well tolerated by all subjects,

[Analysis of the association of diet energy from macronutrients and prevalence of overweight and obesity among the Russian population]

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The fundamental cause for the development of overweight and obesity in adults is a positive balance of energy. However, many environmental factors can contribute to or restrain the development of obesity. These, of course, include the composition of the diet and the structure of its energy value.

[Carbohydrate-related nutritional and genetic risks of obesity for indigenous northerners].

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By the end of the 2010-s the prevalence of obesity among the indigenous people of the North approached to the all-Russia one and the speed of the spread of other metabolic disorders exceeded the average all-country levels. Aim of this review is to analyze data on the increase in consumption and

Acute effects of low insulinemic sweeteners on postprandial insulin and glucose concentrations in obese men.

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OBJECTIVE This randomized, double-blind, crossover study was designed to assess the effects of trehalose, a non-reducing disaccharide, alone and in combination with fructose, on postprandial serum insulin and glucose levels in obese men compared with a glucose control. METHODS Participants (n=21)

Influence of total sugar intake on metabolic blood markers at 8 years of age in the Childhood Obesity Project.

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We aimed to characterize the association of dietary sugar intake with blood lipids and glucose-related markers in childhood.Data from the multicentric European Childhood Obesity Project Trial were used. Three-day weighed dietary records were obtained at 8

Rare mono- and disaccharides as healthy alternative for traditional sugars and sweeteners?

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Obesity and type 2 diabetes are major health problems affecting hundreds of millions of people. Caloric overfeeding with calorie-dense food ingredients like sugars may contribute to these chronic diseases. Sugar research has also identified mechanisms via which conventional sugars like sucrose and

The effect of high-fructose corn syrup consumption on triglycerides and uric acid.

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Rates of overweight and obesity have been on a steady rise for decades, and the problems society faces from this and associated metabolic diseases are many. As a result, the need to understand the contributing factors is great. A very compelling case can be made that excess sugar consumption has

Weight change in relation to intake of sugar and sweet foods before and after weight reducing gastric surgery.

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OBJECTIVE To test the hypothesis that a diet containing many sweet foods is associated with poor weight loss after gastroplasty. METHODS 375 severely obese subjects followed for 2 y after vertical banded gastroplasty or gastric banding; 34 subjects followed after gastric bypass. RESULTS Total energy

Continuous intake of Trehalose induces white adipose tissue Browning and Enhances energy metabolism.

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Trehalose is well known as a functional disaccharide with anti-metabolic activities such as suppression of adipocyte hypertrophy in mice and alleviation of impaired glucose tolerance in humans. Recently, a new type of adipocyte beige cells, involved in so-called white adipocyte tissue

An extract of black, green, and mulberry teas causes malabsorption of carbohydrate but not of triacylglycerol in healthy volunteers.

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BACKGROUND In vitro studies suggest that extracts of black, green, and mulberry teas could interfere with carbohydrate and triacylglycerol absorption via their ability to inhibit alpha-amylase, alpha-glucosidase, sodium-glucose transporters, and pancreatic lipase. OBJECTIVE We measured breath

[Sugar content in non-alcoholic beverages and dietary recemmendations for children and adolescents].

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BACKGROUND Increase the intake of sugars among the inhabitants of developed countries is related to, among others, increasing consumption of non-alcoholic beverages, for which the relationship with the epidemic of obesity, particularly among children and adolescents, has been proven. The most

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