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Страница 1 от 30 резултата
[Effect of ephedrine on nasal cavity mucosa and study on therapy of ATP to the effect].
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OBJECTIVE
To observe the effects of ephedrine on histomorphology and ultrastructure of nasal cavity mucosa from the healthy SD rats and explore the intervenient role of adenosine triphosphate(ATP).
METHODS
Twenty-three SD rats were divided randomly into three groups: Group A as control group; Group
Evaluation of effect of ephedrine on the transport of drugs from the nasal cavity to the systemic circulation and the central nervous system.
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It has been shown that vasoconstrictive drugs such as ephedrine derivatives are able to decrease systemic absorption of drugs administered by mucosal surfaces. The present paper set out to evaluate in the rat model the effect of co-administered nasal ephedrine on the absorption of GR138950 in a
[EXPERIMENTAL CLINICAL TESTING OF N-HYDROXYETHYLPROMETHAZINE CHLORIDE (APROBIT) COMBINED WITH EPHEDRINE HYDROCHLORIDE IN THE NASAL CAVITY].
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Effect of nicotine and ephedrine on the accumulation of 18F-FDG in brown adipose tissue.
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This study evaluated the effect of various beta-adrenergic agonists on (18)F-FDG uptake in brown adipose tissue (BAT) in rats using ex vivo biodistribution studies.
METHODS
Caffeine (10 mg/kg of body weight, n = 4), ephedrine (5 mg/kg of body weight, n = 4), nicotine (0.8 mg/kg of body weight, n =
Urinary excretion of ephedrine after nasal application in healthy volunteers.
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The urinary excretion of ephedrine after intranasal administration of the drug was studied in 8 healthy volunteers. Ephedrine (6 drops of a commercial 0.75% nasal ephedrine solution in each nasal cavity) was administered 4 times at intervals of 2 h (total amount applied equivalent to approximately
[The clinical application of Ephedrine Test in acoustic rhinometry].
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OBJECTIVE
To discuss the clinical application of Ephedrine Test in acoustic rhinometry, we studied the method of quantitative evaluation for nasal mucosal state and discriminated the objective parameters between simple rhinitis and hypertrophic rhinitis.
METHODS
Nasal cavity of volunteers from
Resolution of ephedrine derivatives by means of neutral and sulfated heptakis(2,3-di-O-acetyl)beta-cyclodextrins using capillary electrophoresis and nuclear magnetic resonance spectroscopy.
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Beta-cyclodextrin (beta-CD), heptakis(2,3-di-O-acetyl)beta-cyclodextrin (Diac-beta-CD) and heptakis (2,3-di-O-acetyl-6-sulfato)beta-cyclodextrin (HDAS-beta-CD) were tested for their ability to discriminate the enantiomers of ephedrine, pseudoephedrine, norephedrine and methylephedrine. Using
Study on the chiral recognition of the enantiomers of ephedrine derivatives with neutral and sulfated heptakis(2,3-O-diacetyl)-beta-cyclodextrins using capillary electrophoresis, UV, nuclear magnetic resonance spectroscopy and mass spectrometry.
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The enantiomers of methylephedrine, pseudoephedrine and ephedrine showed a different migration behavior in capillary electrophoresis in the presence of beta-cyclodextrin (beta-CD), heptakis(2,3-O-diacetyl)-beta-cyclodextrin and heptakis(2,3-O-diacetyl-6-sulfato)-beta-cyclodextrin (HDAS). Utilizing
Effect of cyclodextrins on the hydrolysis of an oxazolidine prodrug of (1R,2S)-(-)-ephedrine-cis-2-(4-methoxyphenyl)-3, 4-dimethyl-5-phenyloxazolidine.
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Molecular complexes of an oxazolidine prodrug of (-)-ephedrine, cis-2-(4-methoxyphenyl)-3,4-dimethyl-5-phenyloxazolidine, with alpha-, beta-, dimethyl-beta- (DM-beta-) and hydroxypropl-beta- (HP-beta-) cyclodextrins (CDs) were examined using ionspray mass spectrometry. The results suggest, under our
Molecularly imprinted films of acrylonitrile/methyl methacrylate/acrylic acid terpolymers: influence of methyl methacrylate in the binding performance of L-ephedrine imprinted films.
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Molecularly imprinted polymeric films (MIPFs) highly selective to 1R,2S(-)ephedrine (L-ephedrine, EPD) were produced by phase inversion post-polymerization imprinting on poly(acrylonitrile-co-methyl methacrylate-co-acrylic acid) (PAMA) terpolymers. The inclusion of methyl methacrylate (MMA) to the
Effect of the solute molecular structure on its enantioresolution on cellulose tris(3,5-dimethylphenylcarbamate).
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The effects of the molecular structures for 13 structurally similar chiral solutes on their HPLC retention and enantioresolutions on a commercially important polysaccharide-based chiral stationary phase, cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC) are studied. Among these 13 solutes, only
[Preliminary clinical observation on treatment of chronic rhinitis with rhinitis spray].
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OBJECTIVE
To investigate the clinical effect of Rhinitis Spray (RS) in treating chronic rhinitis.
METHODS
Eighty patients with chronic rhinitis were divided into three groups, and treated with RS, ephedrine and normal saline respectively.
RESULTS
The short-term effective rate in the three groups was
[Reversible pulmonary arterial hypertension after medication of aminorexfumarate (author's transl)].
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It is reported on a patient who 8 years ago and 42 developed a primary pulmonary arterial hypertension after medication with medicaiton with aminorefumarate, an antiappetizing compound whose structure is similar to ephedrine. A control measurement of the pulmonary artery pressure 8 years later
Do we know the mechanism of chiral recognition between cyclodextrins and analytes?
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The resolution of chiral phenethylamine analogue compounds were studied in presence of single-isomer neutral and negatively charged cyclodextrins (CDs) by means of capillary electrophoresis (CE) and NMR spectroscopy. Whereas the native beta-CD and heptakis(2-N,N-dimethylcarbamoyl)beta-cyclodextrin
Management of Acute Withdrawal and Detoxification for Adults who Misuse Methamphetamine: A Review of the Clinical Evidence and Guidelines
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Methamphetamine is a highly addictive drug that is created illegally in clandestine laboratories using a variety of household chemicals, including ephedrine or pseudoephedrine, that is extracted from over the counter medications.1 There is no legally available alternative drug.
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