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gamma coniceine/conium
Линкът е запазен в клипборда
Страница 1 от 16 резултата
Stereoselective potencies and relative toxicities of γ-coniceine and N-methylconiine enantiomers.
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γ-Coniceine, coniine, and N-methylconiine are toxic alkaloids present in poison hemlock (Conium maculatum). We previously reported the comparison of the relative potencies of (+)- and (-)-coniine enantiomers. In this study, we synthesized γ-coniceine and the enantiomers of N-methylconiine and
Hemlock Alkaloids in Aloes. Occurrence and Distribution of gamma-Coniceine.
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The hemlock alkaloid gamma-coniceine was identified in a number of ALOE species, namely A. GILLILANDII, Reynolds A. BALLYI Reynolds, A. RUSPOLIANA Baker, A. IBITIENSIS Perrier and A. DELTOIDEODONTA Baker. Coniine was identified in A. VIGUIERI Perrier. The levels of gamma-coniceine are higher than
Enzymic synthesis of γ-coniceine in Conium maculatum chloroplasts and mitochondria.
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Further studies of the transaminase responsible for the first committed step in alkaloid formation in Conium maculatum have shown the L-alanine: 5-ketooctanal transaminase to occur in both the mitochondria and chloroplast. Experiments suggest that these enzymes are the isoenzymes Transaminase A and
Proceedings: Alkaloid biosynthesis and gamma-coniceine reductase in Conium maculatum L.
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Biosynthesis of Conium alkaloids using carbon-14 dioxide. Interrelation of gamma-coniceine, coniine, and n-methylconiine.
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Hemlock alkaloids from Socrates to poison aloes.
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Hemlock (Conium maculatum L. Umbelliferae) has long been known as a poisonous plant. Toxicity is due to a group of piperidine alkaloids of which the representative members are coniine and gamma-coniceine. The latter is the more toxic and is the first formed biosynthetically. Its levels in relation
Congenital skeletal malformations induced by maternal ingestion of Conium maculatum (poison hemlock) in newborn pigs.
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Skeletal malformations were induced in newborn pigs from gilts fed Conium maculatum seed or plant during gestation days 43 through 53 and 51 through 61. The teratogenic effects in groups dosed during gestation days 43 through 53 were more severe than those in groups dosed during the later period,
Toxicosis in dairy cattle exposed to poison hemlock (Conium maculatum) in hay: isolation of Conium alkaloids in plants, hay, and urine.
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Cattle in two herds developed signs of bloating, increased salivation and lacrimation, depression, respiratory distress, ataxia, and death after ingestion of hay that contained large amounts of poison hemlock (Conium maculatum). Twenty of 30 Angus cows and calves were affected in the first herd (2
Induction of cleft palate in newborn pigs by maternal ingestion of poison hemlock (Conium maculatum).
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Cleft palates were induced in newborn pigs of gilts fed Conium maculatum seed or plant during gestation days 30 through 45. Twelve of 23 newborn pigs born to 3 gilts given Utah-grown C maculatum seed and 9 of 12 newborn pigs born to a single gilt given the fresh Utah spring-growth C maculatum plant
Lupines, poison-hemlock and Nicotiana spp: toxicity and teratogenicity in livestock.
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Many species of lupines contain quinolizidine or piperidine alkaloids known to be toxic or teratogenic to livestock. Poison-hemlock (Conium maculatum) and Nicotiana spp. including N. tabacum and N. glauca contain toxic and teratogenic piperidine alkaloids. The toxic and teratogenic effects from
Toxicoses in livestock from the hemlocks (Conium and Cicuta spp.).
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The hemlocks, Conium maculatum (poison-hemlock) and Cicuta spp. (waterhemlock), are poisonous plants that cause sizeable losss to the livestock industry. Clinical signs of poisonhemlock toxicosis are similar in all species of livestock and include muscular weakness, incordination, trembling, initial
The killer of Socrates: Coniine and Related Alkaloids in the Plant Kingdom.
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Coniine, a polyketide-derived alkaloid, is poisonous to humans and animals. It is a nicotinic acetylcholine receptor antagonist, which leads to inhibition of the nervous system, eventually causing death by suffocation in mammals. Coniine's most famous victim is Socrates who was sentenced to death by
Poison hemlock (Conium maculatum L.).
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One of the most poisonous species amongst higher plants is Conium maculatum. It is a very common nitrophile weed species, belonging to the Apiaceae (formerly Umbelliferae) family. It contains some piperidine alkaloids (coniine, N-methyl-coniine, conhydrine, pseudoconhydrine, gamma-coniceine), which
Biochemistry of hemlock (Conium maculatum L.) alkaloids and their acute and chronic toxicity in livestock. A review.
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The literature on Conium maculatum biochemistry and toxicology, dispersed in a large number of scientific publications, has been put together in this review. C. maculatum is a weed known almost worldwide by its toxicity to many domestic animals and to human beings. It is an Umbelliferae,
Antifeedant compounds from three species of Apiaceae active against the field slug, Deroceras reticulatum (Muller).
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Extracts of volatiles from foliage of three plants in the Apiaceae, Conium maculatum L. (hemlock), Coriandrum sativum L. (coriander), and Petroselinum crispum Mill. (Nym.) (parsley), previously shown to exhibit antifeedant activity in assays with the field slug, Deroceras reticulatum (Muller)
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