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glycyrrhizic acid/кръвоизлив

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СтатииКлинични изследванияПатенти
7 резултата

Glycyrrhizic acid confers neuroprotection after subarachnoid hemorrhage via inhibition of high mobility group box-1 protein: a hypothesis for novel therapy of subarachnoid hemorrhage.

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Subarachnoid hemorrhage usually results in poor clinical outcome and devastating neurological deficits. The early brain injury and delayed vasospasm after subarachnoid hemorrhage (SAH) are involved in the poor prognosis to the patients, while the mechanisms have not been well elucidated. Previous

Glycyrrhizic acid exerts anti-inflammatory effect to improve cerebral vasospasm secondary to subarachnoid hemorrhage in a rat model.

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This study aimed to investigate the therapeutic effect of glycyrrhizic acid (GA) on the cerebral vasospasm (CVS) in a rat subarachnoid hemorrhage (SAH) model and to explore the potential mechanism. A total of 44 healthy male rats were randomly assigned into 3 groups: control group (n = 12), SAH

Glycyrrhizic acid modulates the atrazine-induced apoptosis in rabbit spleen.

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Atrazine (ATR) is a common herbicide used worldwide. It is a potent endocrine disruptor that causes hormonal imbalance. We investigated the modulatory role predisposed by glycyrrhizic acid (GA) against the hazardous effects caused by the ATR in the rabbit spleen. Sixty rabbits were assigned into 4

The effect of glycyrrhizic acid on traumatic spinal cord injury in rats.

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Spine injury associated with traumatic spinal cord injury eventuates in oxidative stress, inflammation and neuronal apoptosis. The aim of this study is to find out whether the glycyrrhizic acid treatment protects spinal cord from traumatic injuries in rats. To this end, the rats were divided into

Early release of high-mobility group box 1 (HMGB1) from neurons in experimental subarachnoid hemorrhage in vivo and in vitro.

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BACKGROUND Translocation of high-mobility group box 1 (HMGB1) from nucleus could trigger inflammation. Extracellular HMGB1 up-regulates inflammatory response in sepsis as a late mediator. However, little was known about its role in subarachnoid hemorrhage-inducible inflammation, especially in the

Licorice consumption as a cause of posterior reversible encephalopathy syndrome: a case report.

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BACKGROUND A 49-year-old woman was admitted to our hospital because of thunderclap headache and blurred vision. At the time of presentation, her blood pressure was 219/100 mmHg, her arterial pH was 7.64 and her potassium level was 2.7 mM/l. METHODS The combination of sequential computed tomography

Teratogenicity study of ammonium glycyrrhizinate in the Sprague-Dawley rat.

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Ammonium glycyrrhizinate (AG), a commercially used salt of glycyrrhizic acid, was administered in the drinking-water to Sprague-Dawley rats on days 7-17 of pregnancy. The actual intakes were 0, 21.33 +/- 1.22, 238.75 +/- 17.50 and 679.94 +/- 69.87 mg AG/kg body weight/day for groups 0, 1, 2 and 3,
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