COVID

Sars-CoV2

Hydroxychloroquine:
Days 1-14: 3 tabs (600 mg total daily dose)
Azithromycin:
Day 1: 2 tabs (500 mg total daily dose) Days 2-5: 1 tab (250 mg total daily dose)

Hydroxychloroquine and Azithromycin

Ivermectin:
Days 1-2: Weight < 75kg: 4 tabs (12 mg total daily dose) Days 1-2: Weight > 75kg: 5 tabs (15 mg total daily dose)

Ivermectin

Days 1-14: 2 tab TID after a meal (600 mg total daily dose)

Camostat Mesilate

Days 1-14: tea or coffee pod TID (1350 mg total daily dose)

Artemesia annua

University of Kentucky Markey Cancer Center

Novel Agents for Treatment of High-risk COVID-19 Positive Patients

Randomized, Multi-arm Phase II Trial of Novel Agents for Treatment of High-risk COVID-19 Positive Patients

Proportion of patients experiencing clinical deterioration. Clinical deterioration is defined as a less than a 2-point change from the initial COVID 7-Point Ordinal Outcomes Scale within 14 days from the study start. This scale ranges from 1-7. Lower scores indicate worse outcomes (death); higher scores indicate fewer symptoms and better outcomes.

The change in (clearance of) viral RNA will be measured by PCR testing at days 1, 14, 28, and 40 days.

Percentage of patients that experience severe respiratory or other organ failure.

Percentage of patients requiring ICU admission or ventilation.

Clinical status will be assessed using the COVID 7-Point Ordinal Outcomes Scale. This scale ranges from 1-7. Lower scores indicate worse outcomes; higher scores indicate fewer symptoms and better outcomes.

Percentage of patients who have died by day 14.

Percentage of patients experiencing severe adverse events, defined as grade 3 non-hematologic or greater by DMID Toxicity Scale for Determining Severity of Adverse Events.

Number of days patients do not require oxygen supplementation.

Number of days patients do not require mechanical ventilation.

Number of days patients do not require vasopressor treatment.

Number of days patients do not require ICU services.

Number of days patients do not require hospitalization.

Proportion of patients meeting Hy's law criteria.

Proportion of patients with changes in the following liver function tests:
Any ALT or AST ≥ 5 x ULN;
any AST or ALT ≥ 3 x ULN together with the appearance of fatigue, nausea, vomiting, right upper quadrant pain or tenderness, fever, rash and/or eosinophilia (eosinophil percent or count above the ULN);
Persistent ALT ≥ 3 x ULN for a period of more than 4 weeks

Proportion of patients with significant changes in ECG findings, including heart rate, ECG intervals (PR, QTcB, QTcF), conduction changes, or abnormalities including severe QTc prolongation of > 500 ms.

Susanne Arnold

Professor

All patients underwent extensive evaluation:
- Body composition, Diabetes; dyslipidemia, hemoconcentration, hypertension, exercise capacity: 6-Minute Walk test procedure, renal function, inflammatory markers, cause and place of death, time tracking concentrator, quality of life and pulmonary Function.

Chronic Obstructive Pulmonary Disease and Allied Conditions

The Global Initiative for Chronic Obstructive Lung Disease (GOLD) works with health care professionals and public health officials to raise awareness of Chronic Obstructive Pulmonary Disease (COPD) and to improve prevention and treatment of this lung di

Predictors of Mortality in Patients With Advanced Lung Disease in Home Oxygen Therapy

Evaluate the results of evaluations carried out in patients who died and had advanced lung disease diagnosis in use of home oxygen, compared to patients who did not die and the normal population

Assess the amount of oxygen that was used by patients during treatment indication and measurement of variable

Measure the quality of life of these patients and compared with the normal population and patients who died and had survival for longer period

Search the causes of death of these patients and the place to compare with the current epidemiology and relate to the main disease

hemoptysis/затлъстяване

Novel Agents for Treatment of High-risk COVID-19 Positive Patients

Predictors of Mortality in Patients With Advanced Lung Disease in Home Oxygen Therapy

Най-пълната база данни за лечебни билки, подкрепена от науката