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Страница 1 от 118 резултата
Proton Pump Inhibitors versus Histamine-2 Receptor Antagonists and Risk of Pneumonia in Patients with Acute Stroke.
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BACKGROUND
Pneumonia is a serious complication of stroke. Several studies have indicated that certain gastric acid suppressants may be associated with an increased risk of pneumonia in hospitalized patients. However, the association between type of acid suppressant and pneumonia in acute stroke
Histamine H2-Blocker and Proton Pump Inhibitor Use and the Risk of Pneumonia in Acute Stroke: A Retrospective Analysis on Susceptible Patients.
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BACKGROUND
Although histamine H2-blockers (H2B) and proton pump inhibitors (PPI) are used commonly to prevent gastrointestinal bleeding in acute stroke, they are implicated in the increased risk of pneumonia in other disease populations. In acute stroke, the presence of distinctive risk factors of
[State of serotonin--monoamine oxidase and histamine--diamine oxidase systems in circulating blood in ischemic strokes].
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The serotonin-monoamine oxidase and histamine-diamine oxidase systems in the arteria and venous blood of the brain were examined in 65 patients with ischemic cerebral stroke. The examinations have shown that in the acute period of the disease the metabolism of serotonin and histamine is disturbed,
[Dynamics of the histamine content and diamine oxidase activity of the blood in patients with ischemic stroke and transient disorders of cerebral blood circulation].
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Ninety-four patients with acute impairments of the cerebral circulation (AICC) were studied for the activity of diamine oxidase and histamine levels in the blood. It was found for the first time ever that the activity of diamine oxidase was reduced in the precrisis period and in the first hours of
Age-dependent involvement of gut mast cells and histamine in post-stroke inflammation
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Background: Risk of stroke-related morbidity and mortality increases significantly with age. Aging is associated with chronic, low-grade inflammation, which is thought to contribute to the poorer outcomes after stroke seen in the elderly. Histamine (HA) is a major
Stroke induces histamine accumulation and mast cell degranulation in the neonatal rat brain.
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Inflammatory processes are a major cause of hypoxic-ischemic brain damage. The present study focuses on both the cerebral histamine system and mast cells in a model of transient focal ischemia induced by permanent left middle cerebral artery, and homolateral transient common carotid artery occlusion
Neuroimmune Crosstalk in CNS Disorders: The Histamine Connection.
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The neuroimmune system represents a dense network of biochemical signals associated with neurotransmitters, neuropeptides, neurohormones, cytokines, chemokines, and growth factors synthesized in neurons, glial cells and immune cells, to maintain systemic homeostasis. Endogenous and/or exogenous,
[Changes in the histamine concentration, histaminase activity and histaminopexic index of the blood in acute cerebral circulatory disorders].
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In 67 patients with ischemic and hemorrhagic strokes the authors studied the histamine metabolism in its development correlating the observed changes (in the acute stage of the disease and following medicative therapy). The results demonstrated that in the acute period of the disease the histamine
Inhibition of CD203c membrane up-regulation in human basophils by high dilutions of histamine: a controlled replication study.
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OBJECTIVE
Previous research suggests that human basophil activation may be inhibited by histamine even at extremely low doses (high dilutions). However, uncertainties about the nature of the phenomenon and its reproducibility mean that further, rigorously controlled studies are
Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs.
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1. The effect of the selective histamine H3 receptor agonist, R-alpha-methylhistamine given intravenously (10-100 micrograms kg-1) was examined on baseline total peripheral resistance (TPR), and cardiovascular haemodynamics in bilaterally vagotomized, anaesthetized guinea-pigs. 2.
Tissue blood flow and distribution of cardiac output in cats: changes caused by intravenous infusions of histamine and histamine receptor agonists.
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1 The effects of infusions of histamine on blood pressure, cardiac output, heart rate, total peripheral resistance, stroke volume and tissue blood flow have been determined in anaesthetized cats using radio-active microspheres to measure cardiac output and tissue blood flow.2 Histamine caused
Cardiac mast cells regulate myocyte ANP release via histamine H2 receptor in beating rabbit atria.
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It has been shown that histamine inhibits atrial natriuretic peptide (ANP) release. Because cardiac mast cells are the principal source of histamine in the heart, we hypothesized that cardiac mast cells are involved in the regulation of atrial ANP release. To test the hypothesis, experiments were
CO2 elimination by high-frequency oscillations in dogs--effects of histamine infusion.
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Effective gas exchange can be achieved in normal dogs by ventilation at frequencies of 4-20 Hz using stroke volumes (SV) smaller than the anatomic dead space. CO2 elimination is largely a function of tracheal SV-frequency product (Vosc) in anesthetized, paralyzed dogs with normal lungs. To determine
The inhibitory effect of simvastatin and aspirin on histamine responsiveness in human vascular endothelial cells.
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Statins and aspirin deliver well-established cardiovascular benefits resulting in their increased use as combined polypills to decrease risk of stroke and heart disease. However, the direct endothelial effect of combined statin/aspirin cotreatment remains unclear. Histamine is an inflammatory
Cardiovascular response to histamine during normoxaemia and hypoxaemia in piglets.
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The cardiovascular effects of exogenously administered histamine were investigated in conscious newborn piglets aged 10-11 days during normoxia (21% (v/v) O2) and during isocapneic alveolar hypoxia (10% O2, 3% CO2, 87% N2) to determine its influence on preexisting vascular tone. In the first set of
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