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Diarrhea is a common dose-limiting toxicity associated with cancer chemotherapy, in particular for drugs such as irinotecan (CPT-11), 5-fluouracil, oxaliplatin, capecitabine and raltitrexed. St. John's wort (Hypericum perforatum, SJW) has anti-inflammatory activity, and our preliminary study in the
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BACKGROUND
Hypericum perforatum Linn. (Hypericaceae) (St. John's wort) attenuates opium withdrawal signs.
OBJECTIVE
To explore the therapeutic potential of Hypericum perforatum in the management of opium-induced withdrawal syndrome.
METHODS
The effect of the Hypericum perforatum hydro-ethanol
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St John's wort (Hypericum perforatum) is a medicinal plant used in the treatment of depression and other psychiatric disorders. In the present paper, the toxicity of H. perforatum administered to female rats during the period of organogenesis (day 9-15 of pregnancy) was evaluated. Thirty inseminated
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BACKGROUND
Saint John's wort (Hypericum perforatum) is a medicinal plant used in the treatment of depression and other psychiatric disorders.
OBJECTIVE
In the present paper, the toxicity of H. perforatum administered to female rats during organogenesis (9th to 15th day of pregnancy) was
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BACKGROUND
Recent interest in and evidence for the efficacy of St. John's wort (Hypericum perforatum) for the treatment of mild-to-moderate depression has led to speculation about its efficacy in other disorders. Hypericum's mechanism of action is postulated to be via inhibition of the synaptosomal
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Hypericum sampsonii is an important medicinal plant used in Vietnam to treat many diseases such as backache, burns, diarrhea, and swelling. In order to study the chemical constituents in the aerial parts of H. sampsonii, five compounds, including two xanthones (1-2), and three benzophenones (3-5)
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Hypericin is a natural derivative of the common St. Johns wort plant, Hypericum perforatum. It has in vitro activity against several viruses, including bovine diarrhea virus, a pestivirus with structural similarities to hepatitis C virus (HCV). We conducted a phase I dose escalation study to
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Depression is a common condition, representing close to 6% of visits to primary care providers. Although minorities are more likely to have chronic depression, they are more likely to be incorrectly diagnosed and less likely to receive treatment when compared to the mainstream population. Screening
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BACKGROUND
The use of medicinal plants is an option for livestock farmers who are not allowed to use allopathic drugs under certified organic programs or cannot afford to use allopathic drugs for minor health problems of livestock.
METHODS
In 2003 we conducted semi-structured interviews with 60
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