hypocapnia/възпаление

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[Effect of hypocapnia/alkalosis on the fluid filtration rate in isolated and perfused rabbit lungs].

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Hypocapnia/alkalosis is a consequence of several lung and metabolic pathologies. The aim of this study was to determine whether the increase of fluid filtration rate (FFR) that occurs during Hypocapnia/alkalosis circumstances is determined by hypocapnia, alkalosis or both. 7 groups were formed

Repeated hyperventilation causes peripheral airways inflammation, hyperreactivity, and impaired bronchodilation in dogs.

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Winter athletes have an increased incidence of asthma, suggesting that repetitive hyperventilation with cold air may predispose individuals to airways disease. We used a canine model of exercise-induced hyperpnea to examine the effects of repeated hyperventilation with cool, dry air (i.e., dry air

Blood acid-base changes during acute experimental inflammation in rats.

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Acidosis has often been reported in inflamed tissues, and changes in strong relevant ions at the site of inflammation may provoke alterations in blood acid-base status. We measured changes in blood acid-base variables during carrageenan-induced inflammation in rats. We found a mixed acid-base

[Effect of hypercapnia on the clinical prognosis and severity of infection in patients with severe community-acquired pneumonia]

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Objective: To investigate the effect of hypercapnia at admission on the clinical prognosis and the severity of infection in patients with severe community-acquired pneumonia (SCAP). Methods:

Effects of Volume Guaranteed Ventilation Combined with Two Different Modes in Preterm Infants.
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BACKGROUND Volume-controlled ventilation modes have been shown to reduce duration of mechanical ventilation, incidence of chronic lung disease, failure of primary mode of ventilation, hypocarbia, severe intraventricular hemorrhage, pneumothorax, and periventricular leukomalacia in preterm infants

[The role of psychic factors in the pathogenesis of bronchial asthma].
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Bronchial asthma is a chronic inflammatory disorder of the airways in which many cells play a role, in particular mast cells, eosinophils, neutrophils, T-lymphocytes and epithelial cells. In susceptible individuals this inflammation causes recurrent episodes of wheezing, breathlessness, chest

Sleep apnoea in heart failure: To treat or not to treat?
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Heart failure (HF) and sleep apnoea are common disorders which frequently coexist. Two main types of apnoea occur: one is obstructive which, through recurring episodes of snoring, hypoxaemia, large negative intra-thoracic pressures and arousals from sleep leading to downstream inflammatory and

[Anesthesia for surgery of degenerative and abnormal cervical spine].
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A feature common to all congenital or inflammatory abnormalities of the cervical spine is an actual or potential reduction in the lumen of the spinal canal. The spinal cord and nerve roots are at risk. During intubation, and positioning the patient on the table, all untoward movements of the

Ambient pCO2 modulates intracellular pH, intracellular oxidant generation, and interleukin-8 secretion in human neutrophils.
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Although neutrophils are a critical component of the inflammatory process, their functional regulation is incompletely understood. Of note, although pCO2 varies physiologically and pathologically in the neutrophilic milieu, its affect on neutrophil biological processes is unresolved. We demonstrate

Volume guarantee ventilation.
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Recognition that volume, not pressure, is the key factor in ventilator-induced lung injury and the association of hypocarbia with neonatal brain injury demonstrate the importance of better control delivered tidal volume. New microprocessor-based ventilator modalities combine advantages of

Volume-targeted ventilation.
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Recognition that volume, not pressure, is the key factor in ventilator-induced lung injury and awareness of the association of hypocarbia and brain injury foster the desire to better control delivered tidal volume. Recently, microprocessor-based modifications of pressure-limited, time-cycled

Volume-targeted ventilation.
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Recognition that volume, not pressure, is the key factor in ventilator-induced lung injury and the association of hypocarbia and brain injury dictate the need to better control delivered tidal volume. Volume-controlled ventilation, though much improved, still suffers from loss of volume due to

Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects.
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BACKGROUND The physiological challenges posed by hypobaric hypoxia warrant exploration of pharmacological entities to improve acclimatization to hypoxia. The present study investigates the preclinical efficacy of sphingosine-1-phosphate (S1P) to improve acclimatization to simulated hypobaric

Alterations in respiratory status: early signs of severe necrotizing enterocolitis.
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BACKGROUND Necrotizing enterocolitis (NEC) presents with well-recognized signs of intestinal inflammation such as bilious vomiting, bloody stool, abdominal distension, and tenderness. The authors observed otherwise unexplained changes in the respiratory status requiring increased respiratory support

Interdisciplinary surveillance of intraventricular haemorrhage associated conditions in infants <1000 g.
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OBJECTIVE Intraventricular haemorrhage (IVH) causes some of the most adverse outcomes in infants with birthweight <1000 g. Incomplete antenatal steroids, acidosis, inflammation, postnatal transfer, delayed surfactant administration, hypothermia, hypotension, hypocapnia, persistent ductus arteriosus

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