laryngeal neoplasms/гадене

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Treatment results of alternating chemoradiotherapy with early assessment for advanced laryngeal cancer: A multi-institutional phase II study.

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OBJECTIVE To evaluate the efficacy and safety of alternating chemoradiotherapy (ACRT) with early assessment of advanced laryngeal cancer. METHODS Patients with stage III or IV glottic or supraglottic squamous cell carcinoma were enrolled. ACRT consisted of two cycles of chemotherapy involving

Safety and radiation-enhancing effect of sodium glycididazole in locoregionally advanced laryngeal cancers previously treated with platinum-containing chemotherapy regimens: A preliminary report.

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OBJECTIVE To determine the safety and radiation-enhancing effect of sodium glycididazole in laryngeal squamous cell carcinoma (stage T3-4,N0-3,M0) with conventional radiotherapy. METHODS Patients with locoregional advanced laryngeal cancer (stage T3-4,N0-3,M0) were included: group 1(control,

[Comparison of the effectiveness of different methods of irradiation using metronidazole as a radiation-sensitizing agent in patients with laryngeal cancer. Controlled clinical studies].

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Randomized controlled clinical trial has been carried out in the Oncology Center in Warsaw and Medical Academy in Lódź to assess the effectiveness of application of Metronidazole as radiosensitizer of hypoxic cells in patients with squamous cell laryngeal cancer treated by Cobalt60 irradiation in

Radiotherapy on the neck nodes predicts severe weight loss in patients with early stage laryngeal cancer.

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OBJECTIVE Although patients with early stage (T1/T2) laryngeal cancer (LC) are thought to have a low incidence of malnutrition, severe weight loss is observed in a subgroup of these patients during radiotherapy (RT). The objective of this study was to evaluate weight loss and nutrition-related

[A phase II study of Futraful suppository in head and neck cancer].

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A phase II study of FT-207 suppository (Futraful Suppository) for head and neck cancer was conducted at the Kagoshima University Hospital Dept. of Otorhinolaryngology and its 6 affiliated hospitals. Forty cases with head and neck cancer were entered in the trial, of which 37 were perfectly

[Taxan induction chemotherapy and concomitant chemoradiotherapy with cisplatin in patients with locally advanced head and neck cancer--early results].

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The growing number of patients with head and neck cancer is a reason to search for new effective treatment strategies. Results of treatment for locally advanced squamous cell head and neck cancer with surgery and/or radiotherapy are still unsatisfactory. During last decade concomitant

Adult pneumococcal meningitis presenting with normocellular cerebrospinal fluid: two case reports.

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BACKGROUND Normocellular bacterial meningitis is rarely observed in adult patients. We here report two cases of adult patients with pneumococcal meningitis with a normal cerebrospinal fluid leukocyte count and review eight other cases in the literature. METHODS Case 1 was a 34-year-old Japanese

Recovery of chronic renal impairment with sirolimus after lung transplantation.

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BACKGROUND Standard immunosuppression after lung transplantation includes calcineurin inhibitors, azathioprine, and steroids. Calcineurin inhibitor administration is associated with an increased renal impairment. Sirolimus shows no renal toxicity and could be used in selected patients. METHODS We

[Clinical analysis of nimotuzumab plus cisplatin and fluorouracil regimen as induction treatment in resectable head and neck squamous cell carcinoma].

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OBJECTIVE A phase II study was conducted to test the efficacy and toxicity of the combination of cisplatin, 5-Fu and nimotuzumab, as induction treatment of resectable head and neck squamous cell carcinoma (HNSCC). METHODS Forty cases of resectable HNSCC were treated with nimotuzumab (400 mg on day

Symptom clusters in patients with head and neck cancer receiving concurrent chemoradiotherapy.

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OBJECTIVE This study is to identify symptom clusters for head and neck (HNC) patients treated with concurrent chemoradiotherapy. METHODS A secondary data analysis of 684 HNC patients treated on the Radiation Therapy Oncology Group (RTOG) 0129 trial comparing different RT fractionation schedules with

Risk factors for clinician-reported symptom clusters in patients with advanced head and neck cancer in a phase 3 randomized clinical trial: RTOG 0129.

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BACKGROUND Chemoradiotherapy has become the standard of care for head and neck squamous cell carcinoma; however, those patients often experience multiple treatment-related symptoms or symptom clusters. Two symptom clusters have been identified for this population. Little is known about the risk

Seizures associated with low-dose tramadol for chronic pain treatment.

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The management of cancer pain still poses a major challenge for clinicians. Tramadol is a centrally acting synthetic opioid analgesic. Its well-known side effects include nausea, vomiting, and dizziness; seizures are a rare side effect. Some reports have found that tramadol triggers seizure activity

Adverse events associated with concurrent chemoradiation therapy in patients with head and neck cancer.

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OBJECTIVE To assess toxicities, functional outcomes, and health-related quality of life associated with concurrent chemoradiation therapy (CRT) in patients with head and neck cancer. METHODS Prospective and retrospective outcomes study. METHODS Tertiary care institution. METHODS Participants in the

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