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Anti-inflammatory activity of Leontopodium alpinum and its constituents.

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The aerial parts and roots of Leontopodium alpinum Cass. (Asteraceae) were investigated for their in vivo topical anti-inflammatory activity using the inhibition of Croton oil-induced ear dermatitis in mice. For both of the plant parts, the dichloromethane extract induced a dose-dependent oedema

Spectrum-effect relationships between high-performance liquid chromatography fingerprints and anti-inflammatory activities of Leontopodium leontopodioides (Willd.) Beauv.

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Leontopodium leontopodioides (Willd.) Beauv. is used therapeutically to prevent numerous diseases. Historically, L. leontopodioides extracts have been used to treat influenza infections, bronchitis, acute and chronic nephritis, proteinuria, hematuria, and diabetes. However, the bioactive compounds

[Effect of Leontopodium leontopodioides (Willd.) Beauv. on inflammation induced by animal reversed passive arthus (RPA)].

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The extract from Leontopodium leontopodioides 50-100mg/kg ip has been proved able to suppress the swelling of normal or adrenalectomised rat hind paws induced by RPA, and strongly inhibit the cutaneous hemorrhage of animals induced by RPA, lysosome or lysosome of broken membrane. It has also been

Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells.

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Edelweiss (Leontopodium alpinum Cass.) is traditionally employed in folk medicine as an anti-inflammatory remedy. In nature, the plant is sparsely available and protected; therefore production of callus cultures was established. A concentrated ethanolic extract of culture homogenate, with

Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling.

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Edelweiss (Leontopodium Alpinum) in the family Asteraceae is a wildflower that grows in rocky limestone places. Here, we investigated the efficacy of edelweiss callus culture extract (Leontopodium Alpinum callus culture extract; LACCE) using multiple assays from in vitro

In vivo efficacy of different extracts of Edelweiss (Leontopodium alpinum Cass.) in animal models.

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Dichloromethane, methanolic and CO(2) extracts of the aerial parts and roots of Edelweiss (Leontopodium alpinum Cass.) were investigated for their anti-inflammatory and analgesic effects after oral administration. The highest activity in rat's paw edema assay was found for the lipophilic extracts of

Antagonistic effects of extracts from Artemisia rupetris L. and Leontopodium leontopodioides to CC chemokine receptor 2b (CCR2b).

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The present study was designed to establish a suitable assay to explore CCR2b receptor antagonists from the natural products of Artemisia rupetris and Leontopodium leontopodioides. An aequorin assay was developed as a cell-based assay suitable for 384-well microplate and used for screening CCR2b

Terpenoids from the roots of Leontopodium longifolium and their inhibitory activity on NO production in RAW264.7 cells.

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Phytochemical investigation of the roots of Leontopodium longifolium, led to the isolation of a novel norsesquiterpene, named as longifolactone (1), along with three known diterpenes. The structures of these compounds were elucidated by analysis of HR-ESI-MS, UV, IR and 1D and 2D NMR spectroscopic

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