macular degeneration/гадене

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Indocyanine green videoangiography of choroidal neovascular membrane in age-related macular degeneration.

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Fluorescein angiography is the traditional tool for the detection of choroidal neovascularization of age-related macular degeneration. However, some limitations exist which impede its efficacy in the detection of subretinal neovascularization. Indocyanine green videoangiography is a recently

Short-term oral pentoxifylline use increases choroidal blood flow in patients with age-related macular degeneration.

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OBJECTIVE To study the ocular hemodynamic effects of a 3-month oral treatment with pentoxifylline in patients with nonexudative age-related macular degeneration. METHODS Double-blind, placebo-controlled, randomized, parallel group study. METHODS Outpatient clinic of the Department of Ophthalmology,

Vascular disrupting agent for neovascular age related macular degeneration: a pilot study of the safety and efficacy of intravenous combretastatin A-4 phosphate.

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BACKGROUND This study was designed to assess the safety, tolerability, and efficacy of intravenous infusion of CA4P in patients with neovascular age-related macular degeneration (AMD). METHODS Prospective, interventional, dose-escalation clinical trial. Eight patients with neovascular AMD refractory

Oral Tyrosine Kinase Inhibitor for Neovascular Age-Related Macular Degeneration: A Phase 1 Dose-Escalation Study.

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UNASSIGNED An oral treatment for neovascular age-related macular degeneration would be less burdensome than repeated intravitreous injections. X-82 is an oral tyrosine kinase inhibitor active against vascular endothelial growth factor (VEGF) and platelet-derived growth factor. UNASSIGNED To

Central Macular Thickness Monitoring after a Taxane-Based Therapy in Visually Asymptomatic Patients.

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BACKGROUND Taxanes are drugs used in various chemotherapeutical protocols to treat solid tumors. They have multiple systemic adverse effects, such as bone marrow suppression, alopecia, nausea, and vomiting, and may rarely cause ocular symptoms. In the past decade, a few reported cases have shown the

Slow versus Rapid Fluorescein Injection in Angiographic Studies for Retinal Vascular Disorders.

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OBJECTIVE To compare the incidence of adverse reactions following rapid versus slow fluorescein injection for fundus angiography. METHODS This randomized controlled trial was performed on 500 patients with retinal vascular disorders. Subjects with central serous retinopathy, age-related macular

Currently available hypolipidaemic drugs and future therapeutic developments.

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Dyslipidaemia may be treated with a number of safe and effective pharmacological agents that target specific lipid disorders through a variety of mechanisms. The bile-acid sequestrants--cholestyramine and colestipol--primarily decrease LDL cholesterol by binding bile acids, thereby decreasing

Bacillus cereus endophthalmitis following intravitreous bevacizumab injection.

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The first case of Bacillus cereus endophthalmitis following an intravitreous injection of bevacizumab is described. A 77-year-old man presented to a retina specialist with an active choroidal neovascularization related to age-related macular degeneration for which he received intravitreous

Spectrum of digoxin-induced ocular toxicity: a case report and literature review.

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BACKGROUND Digoxin intoxication results in predominantly digestive, cardiac and neurological symptoms. This case is outstanding in that the intoxication occurred in a nonagenarian and induced severe, extensively documented visual symptoms as well as dysphagia and proprioceptive illusions. Moreover,

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