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migraine disorders/епилептични припадъци

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Bone microenvironment modulated seizure treatments

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CROSS REFERENCE TO RELATED APPLICATIONS The application is related to application Ser. No. 11/975,465 filed on Oct. 19, 2007 for bone microenvironment modulated migraine treatments. Application Ser. No. 11/975,465 disclosed novel etiology underlying certain types of headaches and migraines, whereby

Method of treating migraine headache without aura

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TECHNICAL FIELD OF THE INVENTION The present invention relates to methods and compositions for treating selected conditions of the central and peripheral nervous systems employing non-synaptic mechanisms. More specifically, one aspect of the present invention relates to methods and compositions for

Cyclohexylamine derivatives as subtype selective N-Methyl-D-Aspartate antagonists

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FIELD OF THE INVENTION The invention provides cyclohexylamine derivatives as N-Methyl-D-Aspartate (NMDA) antagonists, pharmacological compositions comprising the derivatives, and methods of treating diseases and disorders responsive to antagonism of NMDA receptors using the derivatives. BACKGROUND

Nerve stimulation methods for averting imminent onset or episode of a disease

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BACKGROUND OF THE INVENTION The field of the present invention relates to the delivery of energy impulses (and/or fields) to bodily tissues for prophylactic purposes. It relates more specifically to the use of non-invasive devices and methods for transcutaneous electrical nerve stimulation and

Systems, devices and methods for the treatment of neurological disorders and conditions

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TECHNICAL FIELD The present disclosure generally relates to cutaneous neurostimulator systems, devices and methods of using the same and more particularly relates to cutaneous neurostimulator systems, devices and methods for treating or promoting recovery from neurological disorders or conditions,

Systems, devices and methods for the treatment of neurological disorders and conditions

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TECHNICAL FIELD The present disclosure generally relates to cutaneous neurostimulator systems, devices and methods of using the same and more particularly relates to cutaneous neurostimulator systems, devices and methods for treating or promoting recovery from neurological disorders or conditions,

Systems, devices and methods for the treatment of neurological disorders and conditions

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This application is also related to the following copending applications: U.S. application Ser. No. 12/898,685, entitled "Extracranial Implantable Devices, Systems and Methods for Treatment of Neuropsychiatric Disorders," filed on even date herewith with U.S. application Ser. No. 12/898,686,

Digital electromagnetic pulse generator

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable INCORPORATION-BY-REFERENCE OF MATERIAL SUBMITTED ON A COMPACT DISC Not applicable BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates generally to medical equipment for Magnetic Resonance Therapy

Compositions and methods for the treatment of epilepsy and neurological diseases

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PRIORITY The present application claims the benefit of Indian Provisional Patent Application No. 3701/CHE/2012 filed on 6 Sep. 2012 and the International Application No. PCT/IB2013/056683 filed on 16 Aug. 2013, the entire disclosure of which is relied on for all purposes and is incorporated into

Substituted thiomorpholine derivatives

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FIELD OF THE INVENTION The present invention relates to novel substituted morpholine and thiomorpholine derivatives being openers of the KCNQ family potassium ion channels. The compounds are useful in the treatment of disorders and diseases being responsive to opening of the KCNQ family potassium

Substituted dihydro benzocycloalkyloxymethyl oxazolopyrimidinones, preparation and use thereof

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a series of substituted dihydro benzocycloalkyloxymethyl oxazolopyrimidinones. More specifically, the present invention relates to a series of substituted

Substituted dihydro, trihydro and tetrahydro cycloalkyloxazolopyrimidinones, preparation and use thereof

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a series of substituted dihydro, trihydro and tetrahydro cycloalkyloxazolopyrimidinones. More specifically, the present invention relates to a series of 2-substituted-di- tri or

Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a series of substituted dihydro and tetrahydro oxazolopyrimidinones. More specifically, the present invention relates to a series of 2-substituted-2,3-dihydro-oxazolo[3,2-a]pyrimidin-7-ones and

Use of isatin derivatives as ion channel activating agents

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TECHNICAL FIELD The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SK.sub.Ca and IK.sub.Ca channels. In further aspects, the present invention relates to the

4-substituted piperidine analogs and their use as subtype selective NMDA receptor antagonists

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention is related to 4-substituted piperidine analogs, including hydroxypiperidine and tetrahydropyridine analogs, as well as novel intermediates of the 4-substituted analogs. The analogs are selectively active as antagonists of
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