An oligosaccharide containing about 20 monosaccharide units is provided. This oligosaccharide designated (M.sub.9 G).sub.2 is a copolymer .beta.-D-(1.fwdarw.4) connected mannuronopyranose units and an .alpha.-L-(1.fwdarw.4) connected guluronic acid unit at a ratio of 9:1. In addition, 40-60% of the carboxylic functional groups are esterified with propanol, 2-propanol or methanol, and substantially all of the C.sub.2 carbons and about 50% of the C.sub.3 positions of the residues are sulfated, such that the resulting compound contains about 7-13% organic sulfur. The compounds are used for the prevention and therapy of thrombosis-induced ischemic vascular diseases of the heart and the central nervous system, for treating acute thrombosis-induced brain infarction and in coronary ischemia-induced angina, and for treating hyperlipoproteinemia and lowering the relative amount of cholesterol.

Ocean University of Oingdao

Low molecular weight sulfated polysaccharides and uses thereof

Perfluoroalkyl-containing complexes with sugar radicals of general formula I ##STR1## in which R represents a monosaccharide or oligosaccharide radical that is bonded via the 1-OH position or 1-SH position, R.sub.f means a perfluorinated carbon chain, K is a metal complex, and Y and Z represent linker groups, are suitable for intravenous lymphography, for tumor diagnosis and for infarction and necrosis imaging.

monosaccharide/инфаркт

Low molecular weight sulfated polysaccharides and uses thereof

Perfluoroalkyl-containing complexes with sugar radicals, process for their production and their use

Най-пълната база данни за лечебни билки, подкрепена от науката