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Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome

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COVID-19 is a rapidly evolving pandemic with approximately 5% of all patients requiring admission to the intensive care unit. In critically ill patients infected with COVID-19, ARDS is found in 40%, more than 25% require continuous renal replacement therapy, and more than 10% develop vasodilatory

Efficacy of Prebiotic and Probiotic Dietary Modulation in Schizophrenic Disorders

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1. INTRODUCTION 1.1. Theoretical Framework Schizophrenia is a chronic mental illness characterized by significant clinical heterogeneity and a long evolution over time, determined by periods of psychotic exacerbation and phases of stabilization. The semiology of this nosological entity is

Effects of Capacitive Radiofrequency at the Dermis and Adipose Tissue

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In Brazil, the search for satisfaction with self-image has been increasing, since the profile of the population has been altered by cultural factors such as industrialized foods with high caloric content and sedentary lifestyle. These factors result in the accumulation of adipose tissue in typical

"The Effect of Stellate Ganglion Block in Severe Brain Injury"

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Hypothesis Stellate ganglion blockade in patients with moderate and severe brain damage: 1. Increases the diameter of the brain arteries and blood flow through the brain 2. Do not interfere with intracranial pressure 3. Reduces aseptic inflammatory reaction of the damaged brains measured by IL-6 and

Evaluation of Intestinal Microbiota Manipulation to Treat Resistant Hypertension

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The gastrointestinal tract begins its colonization shortly after the birth. During the first two years of life, microbiota is unstable and less diverse than in adulthood, when its complexity and diversity are modified. There are more than 100 trillion microorganisms hosted in the gut, mostly as

Therapeutic Plasma Exchange in Adult Patients With Severe Sepsis

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Background The incidence of sepsis has increased over the last four decades (1). Sepsis is a life-threatening condition that arises when the body's response to an infection injures its own tissues and organs. Severe sepsis and septic shock are among the leading causes of death for patients admitted

7-day Atorvastatin and Emotional Processing

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Depression is common and associated with considerable health disability. Traditional antidepressants mainly work by modulating monoamine levels in the synaptic cleft; however, the evidence that depression is caused by impaired serotonin or noradrenaline activity is weak and inconsistent, and indeed

Lactobacillus Reuteri ATCC PTA 4659 in Ulcerative Colitis

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Research question To study whether dietary supplementation with L. reuteri ATCC PTA 4659 (Lr4659) is safe and can reduce the relapse rate and have a positive effect in patients with ulcerative colitis (UC). Lr4659 is a naturally occurring strain of human origin. It is a typical member of the L.

Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

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The dogma over the past 3 decades, particularly in the field of sleep medicine, has been that intermittent hypoxia (IH) is a detrimental stimulus that leads to a number of co‐morbidities including autonomic (e.g. increased sympathetic nervous system activity), cardiovascular (e.g. hypertension,

Erythropoietin Role in Acute Kidney Injury

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Introduction Background and rationale Since the release of the recombinant human erythropoietin (rhuEPO) at the beginning of the 90s, transfusions are less needed to treat anemia in chronic kidney disease patients. This has been a major revolution in the management of renal anemia in chronic kidney

Lactobacillus Plantarum PS128 in Patients With Major Depressive Disorder and High Level of Inflammation

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1. Background Major depressive disorder (MDD) is a complex and long-term illness that involves marked disabilities in affected patients. It has been one of the leading causes of global burden of disease, especially in the middle-age groups (GBD Lancet 2016; 388:1603-58). It is also a common

Plasmaexchange in Early Septic Shock

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Does Propranolol Attenuate Inflammatory Responses to a Psychological Stressor?

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Psychological stress is implicated in the onset and progression of many common and costly chronic diseases, including cardiovascular disease, chronic pain conditions, and major depressive disorder (Cohen et al., 2007; Kendler et al., 1999; Steptoe and Kivimäki, 2012). An emerging body of evidence

On Demand Versus Protocol-guided Renal Replacement Therapy for Management of Stage 3 Acute Kidney Injury in Patients With Cirrhosis

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Effects of Vasopressors on Immune Response

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Rationale: Septic shock is a major medical challenge associated with a high mortality rate and increasing incidence. It has become clear that the majority of septic patients do not succumb to an initial pro-inflammatory "hit", but at a later time-point in a pronounced immunosuppressive state, so

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