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ocimum gratissimum/оток

Линкът е запазен в клипборда
СтатииКлинични изследванияПатенти
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Pharmacological evidence for the folk use of Nefang: antipyretic, anti-inflammatory and antinociceptive activities of its constituent plants.

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BACKGROUND Nefang is a polyherbal anti-malarial composed of Mangifera indica ( MiB and MiL; bark and leaf), Psidium guajava ( Pg ), Carica papaya ( Cp ), Cymbopogon citratus ( Cc ), Citrus sinensis ( Cs ) and Ocimum gratissimum ( Og ) (leaves). Previous studies have demonstrated its in vitro and in

In vivo anti-inflammatory activities of leaf extracts of Ocimum lamiifolium in mice model.

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OBJECTIVE Ocimum lamiifolium Hochst. ex Benth. (Lamiaceae) has been used in Ethiopian traditional medicine for the treatment of different inflammatory disorders such as oropharyngitis, wound, pain, fever, and others. However, its use has mainly been based on empirical findings. Thus the objective of

Ocimum gratissimum Linn. Leaf extract inhibits free radical generation and suppressed inflammation in carrageenan-induced inflammation models in rats.

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BACKGROUND Ocimum gratissimum leaf is used in managing rheumatism and other inflammatory conditions. In this study, we investigated the antioxidant and anti-inflammatory effects of phenolic extract obtained by sequential methanol extraction of O. gratissimum leaves (MEOg). METHODS The methanol

Toxicity and Protective Effect of Phenolic-Enriched Ethylacetate Fraction of Ocimum gratissimum (Linn.) Leaf against Acute Inflammation and Oxidative Stress in Rats.

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Preclinical Research Ocimum gratissimum L. leaves have attracted considerable attention from researchers because of their medicinal value that include anti-inflammatory, analgesic, antimicrobial, and antioxidant activities. In the present study, the toxicity and the protective effect of phenolic

Anti-inflammatory activity of Ocimum americanum L. essential oil in experimental model of zymosan-induced arthritis.

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Essential oils are potential sources of novel components for medicinal use. The present study was performed to investigate the composition and anti-inflammatory activity of Ocimum americanum L. essential oil (OEO) and its components in an experimental model of zymosan-induced arthritis and paw

In vivo anti-inflammatory activities of Ocimum suave in mice.

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BACKGROUND Ocimum suave has been used in the Ethiopian traditional medicine to relieve pain, fever, inflammation and other disease conditions. OBJECTIVE The aim of the present study was to investigate the anti-inflammatory activities of the aqueous and ethanol leaf extracts and some fractions of

Mechanism of action of antiinflammatory effect of fixed oil of Ocimum basilicum Linn.

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Fixed oil of O. basilicum was found to possess significant antiinflammatory activity against carrageenan and different other mediator-induced paw edema in rats. Significant inhibitory effect was also observed in castor oil-induced diarrhoea in rats. It also inhibited arachidonic acid- and

Evaluation of antiinflammatory activity of fatty acids of Ocimum sanctum fixed oil.

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Ocimum sanctum fixed oil and linolenic acid were found to possess significant antiinflammatory activity against PGE2, leukotriene and arachidonic acid-induced paw edema. Plant lipids like linseed oil and soyabean oil containing linolenic acid when tested along with O. sanctum fixed oil, also showed

Chemical and pharmacological studies on fixed oil of Ocimum sanctum.

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Gas liquid chromatographic analysis of fixed oil of O. sanctum revealed the presence of five fatty acids (stearic, palmitic, oleic, linoleic and linolenic acids). The triglyceride fraction of the oil showed higher protection compared to fixed oil against carrageenam-induced paw edema and acetic

Ocimum sanctum: an experimental study evaluating its anti-inflammatory, analgesic and antipyretic activity in animals.

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A methanol extract and an aqueous suspension of Ocimum sanctum inhibited acute as well as chronic inflammation in rats as tested by carrageenan-induced pedal edema and croton oil-induced granuloma and exudate, respectively. In both test procedures, the anti-inflammatory response of 500 mg/kg of

Evaluation of the efficacy of 2% Ocimum sanctum gel in the treatment of experimental periodontitis.

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BACKGROUND One of the options for the treatment of periodontitis is local drug delivery systems (LDD). Tulsi (Ocimum sanctum), a traditional herb, has many uses in medicine. It could be a suitable agent as LDD for the treatment of periodontitis. OBJECTIVE The aim was to formulate, evaluate the

Pharmacological and phytochemical evaluation of Ocimum sanctum root extracts for its antiinflammatory, analgesic and antipyretic activities.

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BACKGROUND Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) increases risk of having a range of gastrointestinal problems. Therefore, new anti-inflammatory, analgesic, antipyretic drugs having lesser side effects are being searched all overthe world as alternatives to

Effect of Ocimum sanctum Linn. on cardiac changes in rats subjected to chronic restraint stress.

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Male Wistar rats were subjected to chronic restraint stress (CRS; 6 h/day for 21 days) alone or along with either hydroalcoholic extract of Ocimum sanctum (Os; 100 mg/kg; orally) or MK-801, an NMDA receptor antagonist (0.3 mg/kg; i.p.). In the rats subjected to only CRS, plasma cAMP level was

Improvement in bioavailability of transdermally applied flurbiprofen using tulsi (Ocimum sanctum) and turpentine oil.

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Penetration enhancing potential of tulsi and turpentine oil on transdermal delivery of flurbiprofen, a potent non-steroidal anti-inflammatory agent, was investigated. The transdermal permeation rate of flurbiprofen across the rat abdominal skin from binary solvent mixture composition of propylene

Comparative evaluation of antiinflammatory potential of fixed oil of different species of Ocimum and its possible mechanism of action.

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Ocimum sanctum fixed oil and linolenic acid found to possess significant antiinflammatory activity against PGE2, leukotriene and arachidonic acid-induced paw edema. The other species of Ocimum, viz. O. basilicum and O. americanum also containing linolenic acid in varying proportions, also showed
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