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The Effect of Curcumin on the Development of Prednisolone-induced Hepatic Insulin Resistance

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AIMS OF STUDY The aim of this study is to investigate whether ingestion of curcumin will prevent hepatic insulin resistance (assessed by homeostatic model assessment of insulin resistance (HOMA-IR)) induced by short-term oral glucocorticoid (prednisolone) administration in overweight and obese

Effectiveness of Curcumin-based Food Supplement in Reducing Pain and Inflammatory Component in Osteoarthritis

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INTRODUCTION Gonarthrosis is the most common disorder of the musculoskeletal system, with an age-related prevalence varying between 12-55%. The treatment of OA is mostly symptomatic and includes the use of analgesics, NSAIDs, exercise and even surgery. However, the use of long-term NSAIDs is

FUSION EVALUATION AFTER ANTERIOR CERVICAL DISCECTOMY AND FUSION WITH STAND ALONE LOCKING CAGE WITH BLADE HRCC®

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Introduction: Cervical degenerative disease is an almost universal concomitant of human aging. Over half of the middle aged population has radiological or pathological evidence of cervical spondylosis. This condition is often asymptomatic, but in 10% to 15% of the cases, it is associated with, or

Prospective Versus Retrospective Complications in Radical Cystectomy and Nephrectomy

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Background: Today there are many different systems to classify co morbidity and complication of radical cystectomy and nephrectomy. Regarding complication, there is Clavien Dindo classifications System and The National Surgical Quality Improvement Program (NSQIP) while Charlson Comorbidity Index

Effect of Periodontitis on Bone Mineral Density in Postmenopausal Women

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Rapid estrogen level decline after menopause is associated with systemic bone loss in women leading to osteopenia/osteoporosis. Estrogen therapy (ET) improves bone mineral density (BMD) in postmenopausal women. Currently, ET has been associated with statistically significant increased risk of breast

Osteomyelitis: Procalcitonin to Diagnose and Monitor Osteomyelitis (PCT)

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Infection: will be defined as a patient with three of six clinical signs of infection (erythema, heat, edema, pain, loss of function, purulence) or leukocytosis. We will use the Infectious Diseases Society of America's Diabetic Foot Infection guidelines to stratify the severity of infection. This

Electrical Stimulation for Improving Balance in Diabetes

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There will be a total of five study visits required for each patient. There will be one scheduled visit for baseline evaluation and four additional visits at 2 weeks, 4 weeks, 6 weeks during treatment and 8 weeks (2 weeks post stopping the treatment). The baseline visit will involve completion of a

Pelvic Fractures and Radiation Therapy for Cervical Cancer

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If you agree to take part in this study, the following tests and procedures will be performed before radiation therapy: - You will have a bone mineral density test. A bone mineral density test measures bone loss over time, identifies osteoporosis (a disease of the bones that causes them to be weak

Health and Psychosocial Outcomes in Long-Term Lymphoma Survivors

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Survival rates for both non-Hodgkin's (NHL) and Hodgkin's lymphoma (HL) have improved in recent years due to the development of better treatments. However, the diagnosis and treatment may leave a cancer survivor with long-term consequences. It is recognized that patients cured of HL have increased

Steroid Induced Osteoporosis in Patients With Systemic Lupus Erythematosus

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In the first part of the study, 150 consecutive patients with a diagnosis of SLE were included in the study. All patients fulfilled the American College of Rheumatology (ACR) revised criteria for the classification of SLE and provided written informed consent. Data collected at the time of study

Heredity and Phenotype Intervention (HAPI) Heart Study

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Nearly one million Americans died of CVD in 1999, and it is predicted that, over one million Americans will have a myocardial infarction (MI) with 650,000 of these experiencing their first MI. Coronary artery disease (CAD) is the leading cause of mortality in the U.S., accounting for 1 of every 5

Bone Health in Gynecologic Cancers-does FOSAVANCE Help?

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Objectives: 1. To evaluate the impact of bisphosphonates on bone mineral density (BMD=primary endpoint) in women with gynecologic malignancies undergoing chemotherapy. 2. To determine if bone loss in women with gynecologic malignancies undergoing chemotherapy is correlated with any of the

Osteoporosis School

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In most randomized trials compliance to medical treatment in osteoporosis is very high, but compliance tends to be considerably inferior in routine treatment compared to scientific trials. This fact is caused by a narrow selection of motivated patients in the randomized trials. Perhaps, the

Determining the Risk Factors Such as Smoking, Alcohol, and Caffeine and Their Association With Osteoporosis in Men

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Primary Hypothesis: Risk factors such as smoking, alcohol, and caffeine are associated with osteoporosis in men. Intervention: None Primary Outcomes: Percent reduction in cross-sectional bone mineral density over time. Study Abstract: The goals of this project are to establish a new cohort of male

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