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6 резултата
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea
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The dogma over the past 3 decades, particularly in the field of sleep medicine, has been that intermittent hypoxia (IH) is a detrimental stimulus that leads to a number of co‐morbidities including autonomic (e.g. increased sympathetic nervous system activity), cardiovascular (e.g. hypertension,
Daily Ginger Drinking and Platelet Function
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Herbal medicine products are dietary supplements that people take to improve their health. Many herbs have been used for a long time for claimed health benefits. They are sold as tablets, capsules, powders, beverages, extracts and fresh or dried plants. Herbal medicines have been associated with
WilL LOWer Dose Aspirin be More Effective Following ACS? (WILLOW - ACS)
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Aspirin has an established role in the treatment of ACS and secondary prevention of ischaemic heart disease. In the landmark trial of aspirin in ACS, ISIS-2 (1988), it conferred a benefit of similar magnitude to thrombolysis. The addition of a second antiplatelet agent (a P2Y12 inhibitor) to aspirin
Early Endoscopy for Acute Upper Gastrointestinal Bleeding in Acute Coronary Syndrome Patients
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Antiplatelet therapy is the cornerstone in the management of patients with ACS. Aspirin interferes platelet aggregation activity by decreasing thromboxane synthesis through inhibition of cyclo-oxygenase (COX) enzymes. Low-dose (75-325mg/day) aspirin has been demonstrated to reduce the risk of
Rosuvastatin for Reduction of Myocardial Damage and Systemic Inflammation During Coronary Angioplasty
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Myocardial necrosis, assessed by creatine kinase-MB (CK-MB) elevation, is relatively frequent after percutaneous coronary intervention (PCI), occurring in up to 40% of cases. Although most patients remain asymptomatic and with no changes in cardiac function, even a mild release of CK-MB is
Does Heme Oxygenase-1 Induction Ameliorate Cardiac Injury After Myocardial Infarction?
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The interventional part of this study is a single centre safety and dose defining pilot study in which patients are allocated to heme arginate infusion for 1 day (hem-1d), heme arginate infusion for 2 days, or heme arginate infusion during 3 days (hem-3d) in consecutive order. So, the three patient
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