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8 резултата
Trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors
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BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates to novel trisubstituted benzotriazole derivatives of formula (I) which are inhibitors of dihydroorotate dehydrogenase. In particular, the invention refers to novel compounds, which inhibits DHODH enzyme activity, to a
Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors
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BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates to novel trisubstituted benzotriazole derivatives of formula (I) which are inhibitors of dihydroorotate dehydrogenase. In particular, the invention refers to novel compounds, which inhibits DHODH enzyme activity, to a
Methods for treating oral cancers with herbal compositions
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BACKGROUND OF THE INVENTIVE SUBJECT MATTER
1. Field of the Inventive Subject Matter
The inventive subject matter relates to novel methods for treating oral cancers, comprising administration of a composition comprising therapeutically effective amounts of supercritical extracts of rosemary,
P450 oxygenases and methods of use
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FIELD OF THE DISCLOSURE
The present disclosure relates to P450 oxygenases, particularly to taxoid 5.alpha.-hydroxylases, and the nucleic acids that encode them, and to methods of using such oxygenase nucleic acids and enzymes, for example, to produce Taxol.TM. (commonly known as paclitaxel) and
Substituted imidazole derivatives and methods of use thereof for treating cancer
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FIELD OF THE INVENTION
This invention is in the field of pharmaceuticals, and relates to compounds and compositions for treating/mitigating cancer and for suppressing tumor growth. The invention also relates to compounds, compositions and methods for the treatment and prevention of diseases of the
IDO inhibitors
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FIELD OF THE INVENTION
The invention relates generally to compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or
Synthesis and biological activities of new tricyclic-bis-enones (TBEs)
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BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention provides novel tricyclic-bis-enone derivatives (TBEs), as well as the process for the preparation of such TBEs, for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis,
Synthesis and biological activities of new tricyclic-bis-enones (TBEs)
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Вход / Регистрация
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention provides novel tricyclic-bis-enone derivatives (TBEs), as well as the process for the preparation of such TBEs, for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis,
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