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panaxadiol/женшен
Линкът е запазен в клипборда
Страница 1 от 43 резултата
[Effects of panaxadiol saponins isolated from Panax notoginseng on intracellular and extracellular calcium].
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Panaxadiol saponins (PDS) contain saponins Panax notoginseng B1 and E. The spontaneous beating induced by isoproterenol in isolated rat right atria and the increase of contractile force induced by Ca2+ in isolated guinea pig colon were inhibited by PDS 75 and 150 micrograms.ml-1, respectively and
An oxepane derivative of panaxadiol from the leaves of Panax notoginseng.
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Hydrolysis of the crude saponin isolated from the leaves of PANAX NOTOGINSENG (Burk.) F. H. Chen yields five sapogenins which are separated by column chromatography. The structures of four of those were elucidated earlier to be panaxadiol, panaxatriol, dammar-20(22)en-3beta, 12beta,26-triol and
Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: Biological activity and structural modification.
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Based on the definite therapeutic benefits, such as neuroprotective, cardioprotective, anticancer, anti-diabetic and so on, the Panax genus which contains many valuable plants, including ginseng (Panax ginseng C.A. Meyer), notoginseng (Panax notoginseng) and American ginseng (Panax quinquefolius
Panaxadiol glycosides that induce neuronal differentiation in neurosphere stem cells.
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Bioassay-guided fractionation, combined with screening based on EGF-responsive neural stem cells (NSCs) differentiation assay, has been used to search for active molecules from Panax notoginseng. Ginsenosides Rg3 (1), Rk1 (2), and Rg5 (3) were identified as potential neurogenic molecules. The
[Effects of Ginseng panaxadiol saponin on proliferation and differentiation of human bone marrow CD34+ cells].
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The study was purposed to investigate the effects of the panaxadiol saponin (PDS) from Ginseng on proliferation and differentiation of human CD34(+) cells from human bone marrow. Highly purified CD34(+) cells were isolated from human bone marrow by using the Dynal CD34 Cell Selection System (Dynal,
Determination of panaxadiol and panaxatriol in ginseng and its preparations by capillary supercritical fluid chromatography (SFC).
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Capillary supercritical fluid chromatographic (SFC) method has been developed for the determination of panaxadiol and panaxatriol in ginseng and its preparations. 0.1 g ginseng or an appropriate amount of its preparations was hydrolysed by 15% H2SO4 in an ethanol:water (1:1 v/v) solution for 4 h
Ginseng-derived panaxadiol saponins promote hematopoiesis recovery in cyclophosphamide-induced myelosuppressive mice: Potential novel treatment of chemotherapy-induced cytopenias.
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OBJECTIVE
To investigate the potential efficacy of panaxadiol saponins component (PDS-C), a biologically active fraction isolated from total ginsenosides, to reverse chemotherapy-induced myelosuppression and pancytopenia caused by cyclophamide (CTX).
METHODS
Mice with myelosuppression induced by CTX
Transcriptional activation of Cu/Zn superoxide dismutase and catalase genes by panaxadiol ginsenosides extracted from Panax ginseng.
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Superoxide dismutase (SOD) converts superoxide radical to H(2)O(2), which is in turn broken down to water and oxygen by catalase. Thus, SOD and catalase constitute the first coordinated unit of defence against reactive oxygen species. A wide variety of chemical and environmental factors are known to
Elicitors' influenced differential ginsenoside production and exudation into medium with concurrent Rg3/Rh2 panaxadiol induction in Panax quinquefolius cell suspensions.
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Cobalt nitrate, nickel sulphate, hydrogen peroxide, sodium nitroprusside, and culture filtrates of Pseudomonas monteili, Bacillus circularans, Trichoderma atroviridae, and Trichoderma harzianum were tested to elicit ginsenoside production in a cell suspension line of Panax quinquefolius. Abiotic
Panaxadiol, a purified ginseng component, enhances the anti-cancer effects of 5-fluorouracil in human colorectal cancer cells.
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OBJECTIVE
Colorectal cancer is a major cause of morbidity and mortality for cancer worldwide. Although 5-fluorouracil (5-FU) is one of the most widely used chemotherapeutic agents in first-line therapy for colorectal cancer, serious side effects limit its clinical usefulness. Panaxadiol (PD) is the
The effects of ginseng total saponin, panaxadiol and panaxatriol on ischemia/reperfusion injury in isolated rat heart.
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The aim of the present study was to evaluate the protective effect of ginseng total saponin, panaxadiol and panaxatriol, which are the major components of Panax ginseng, against myocardial ischemia/reperfusion (I/R) injury in isolated rat hearts. Rats were orally administered once a day with total
[On the sapogenin panaxol or panaxadiol isolated from ginseng root].
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[Chemical studies on ginseng. II. (Studies on asponin-bearing drugs. V.). Some properties of panaxadiol].
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STUDIES ON THE CONSTITUENTS OF JAPANESE AND CHINESE CRUDE DRUGS. XII. PANAXADIOL, A SAPOGENIN OF GINSENG ROOTS.
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[Effect of panaxadiol-saponins from ginseng flowers and leaves on DNA synthesis in mouse ascitic reticulocytic sarcoma cells].
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