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phosphoric acid/рак

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СтатииКлинични изследванияПатенти
12 резултата

Method of treating a cancer by administering A 2',5'-oligoadenylate analog

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to analogs of 2',5'-oligoadenylate (2-5A) that are stable and have superior activity (particularly antitumor activity). 2. Background Art 2-5A, which is known as a biological substance that has antiviral activity

Tumor inhibiting saccharide conjugates

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BACKGROUND OF THE INVENTION In the Federal Republic of Germany, mortality due to cancer ranks second, following cardiovascular diseases, in mortality statistics. Besides surgery and radiation, anti-neoplastic chemotherapy has nowadays become an established cancer therapy. In spite of excellent

Diagnostic agent

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TECHNICAL FIELD The present invention relates to a diagnostic agent to be used in endoscopic observation of the inner wall of a gastrointestine. BACKGROUND ART In observation of the inner wall of a gastrointestine using an endoscope, a procedure in which the observation is made easier by sprinkling

Germanium-containing organic polymer and the process for the production of the same

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to germanium-containing organic polymers which possess important therapeutic effects as medicine. 2. Description of the Prior Art In recent years, attention has been drawn to germanium-containing organic compounds in

Nitroso compounds as nitroxyl donors and methods of use thereof

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable. BACKGROUND OF THE INVENTION Heart Failure Congestive heart failure (CHF) is a generally progressive, life threatening condition in which myocardial contractility is depressed such that the heart is unable to adequately

Nitroso compounds as nitroxyl donors and methods of use thereof

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable. BACKGROUND OF THE INVENTION Heart Failure Congestive heart failure (CHF) is a generally progressive, life threatening condition in which myocardial contractility is depressed such that the heart is unable to adequately

Nitroso compounds as nitroxyl donors and methods of use thereof

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable. BACKGROUND OF THE INVENTION Heart Failure Congestive heart failure (CHF) is a generally progressive, life threatening condition in which myocardial contractility is depressed such that the heart is unable to adequately

Nitroso compounds as nitroxyl donors and methods of use thereof

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable. BACKGROUND OF THE INVENTION Heart Failure Congestive heart failure (CHF) is a generally progressive, life threatening condition in which myocardial contractility is depressed such that the heart is unable to adequately

Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to the formation of a novel, stable C-10 carba trioxane dimer that may easily be transformed into different trioxane dimers. Some of these dimers are 10 times more antimalarially potent in vitro than artemisinin.

Synthesis of combretastatin A-2 prodrugs

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INTRODUCTION This invention generally relates to improved methods of producing antineoplastic compounds and both water-soluble derivatives thereof which retain the same or improved bioactivity as the parent compound, and methods of synthesis thereof. More particularly this invention relates to

Crystalline forms of cabozantinib phosphate and cabozantinib hydrochloride

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This application is a Section 371 national phase entry of PCT application PCT/EP2016/056267, filed Mar. 22, 2016. This application also claims the benefit of the earlier filing date of European patent application 15160869.2, filed Mar. 25, 2015. FIELD OF THE INVENTION The present invention relates

Hydraulic surgical cement

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BACKGROUND OF THE INVENTION This invention concerns a cement for surgical purposes, a method for producing brushite as temporary bone replacement material, and a temporary bone replacement material. A number of such hydraulic cements based on calcium phosphates for use in surgery are known in the
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