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Страница 1 от 170 резултата
Use of quinoline derivatives for treating oesophageal cancer and treatment method, pharmaceutical composition and kit thereof
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CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a U.S. national stage of PCT/CN2017/070352 filed on Jan. 6, 2017, which claims the benefit of Chinese invention patent application No. 20161001628.4 filed on Jan. 8, 2016 in the State Intellectual Property Office of the P. R.
Highly soluble pyrimido-dione-quinoline compounds and their use in the treatment of cancer
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention is directed to pyrimido-dione-quinoline compounds having an improved water solubility, and methods and pharmaceutical compositions that comprise such compounds. Compounds of the invention can be effective to modulate the
Quinoline derivative against non-small cell lung cancer
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CROSS-REFERENCES TO RELATED APPLICATIONS
Incorporation by Reference to any Priority Applications
This application is the U.S. National Phase of International Application PCT/CN2015/096777, filed Dec. 9, 2015, which claims priority and interest of China Patent Application No. 201410749394.0 filed
Imidazo [4,5-C]quinoline derivatives and their use in the treatment of tumors and/or inflammation
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This is a 371 application of PCT/IN2009/052819 filed on Jun. 30, 2009, the content of which is incorporated herein by reference.
FIELD OF THE INVENTION
The present invention relates to imidazo[4,5-c]quinoline derivatives, processes for their preparation, pharmaceutical compositions containing them
Use of quinoline-3-carboxamide compounds for inhibiting the production of tumor necrosis factor (TNF) and/or for the treatment of septic shock
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The present invention concerns the use of quinoline-3-carboxamide compounds, in particular roquinimex (Linomide.RTM.), or a pharmaceutically acceptable salt thereof for inhibiting the production of tumour necrosis factor (TNF) and/or for the treatment of septic shock.
BACKGROUND OF THE
Quinoline derivatives as anti-cancer agents
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FIELD OF THE INVENTION
This invention relates to a novel genus of compounds useful as anti-cancer agents. Particularly, it relates to a group of substituted quinoline derivatives which show potent anti-cancer effects.
BACKGROUND OF THE INVENTION
Substituted quinoline-type alkaloids are known for
Quinoline derivatives having anti-tumor activity
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This invention relates to novel anti-tumour agents and more particularly it relates to quinoline derivatives which possess anti-tumour activity. The invention includes novel quinoline derivatives and processes for their manufacture; novel pharmaceutical compositions containing said quinoline
Method of making and administering quinoline derivatives as anti-cancer agents
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BACKGROUND
Many nitrogen-containing basic and biological active compounds isolated from plants, especially those bearing quinoline moiety, offer a broad spectra of biological activities. For instance, quinine and quinidine are widely used for treatment of malaria and cardiac arrhythmias. Luotonin A
Anti-cancer agents based on N-acyl-2, 3-dihydro-1H-pyrrolo[2,3-b] quinoline derivatives and a method of making
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FIELD OF INVENTION
The present invention relates to novel anti-cancer agents based on derivatives of N-acyl 2,3-dihydro-1H-pyrrolo[2,3-b]quinolines that can be used in prostate cancer therapy. The present invention also relates to methods of preparing said compounds, and to pharmaceutical
[1,3] dioxolo [4,5-G] quinoline-6(5H)thione derivatives as inhibitors of the late SV40 factor (LSF) for use in treating cancer
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The section headings used herein are for organizational purposes only and should not be construed as limiting the subject matter described in any way.
BRIEF DESCRIPTION OF DRAWINGS
The patent or application file contains at least one drawing executed in color. Copies of this patent or patent
Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment
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The present invention concerns aromatic oxidation/hydroxylation activated prodrugs, particularly anti-tumour prodrugs and those which are specifically activated by the oxidation/hydroxylation activities of the cytochrome P450 family of enzymes.
Many conventional cytotoxic drugs are known that can be
Pyrrolo-indole and pyrrolo-quinoline derivatives as prodrugs for tumour treatment
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The present invention concerns aromatic oxidation/hydroxylation activated prodrugs, particularly anti-tumour prodrugs and those which are specifically activated by the oxidation/hydroxylation activities of the cytochrome P450 family of enzymes.
Many conventional cytotoxic drugs are known that can be
Benz-indole and benzo-quinoline derivatives as prodrugs for tumor treatment
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The present invention concerns aromatic oxidation/hydroxylation activated prodrugs, particularly anti-tumor prodrugs and those which are specifically activated by the oxidation/hydroxylation activities of the cytochrome P450 family of enzymes.
Many conventional cytotoxic drugs are known that can be
Substituted quinolines for the treatment of cancer
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CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is the US national stage application of the Patent Cooperation Treaty (PCT) Application Number PCT/EP2004/013106 filed 18 Nov. 2004, entitled "SUBSTITUTED QUINOLINES FOR THE TREATMENT OF CANCER"; which designated all states including
Indolyl-substituted pyrazino-quinolines and their use for the treatment of cancer
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FIELD OF THE DISCLOSURE
This invention relates to novel pharmaceutically-useful compounds, which compounds may be useful in the treatment of cancer. The invention also relates to synthetic methods for preparing the compounds.
BACKGROUND OF THE DISCLOSURE
Cancer is a class of diseases that affects
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