The Intervention group will received multimedia education, booklet and weekly tele-nursing follow-up about chemotherapy and side effects management

The Control group will receive routine care

Chemotherapy Effect

Multimedia education, booklet and weekly tele-nursing follow-up is about chemotherapy and side effects management

Multimedia education, booklet Providence and tele-nursing follow-up

Indus Children Cancer Hospital Karachi

Effect of Nurse-led Education on Parent's Anxiety and Depression on Managing Side Effects of Chemotherapy

Depression (D) and anxiety (A) and stress(S) will be outcome variable. They will be identified by using DASS-21 Scale. The use of DASS-21 Scale is evident in Pakistan . There are 21 questions in this scale equally divided in to three parts having seven questions for Depression, Anxiety and stress respectively. Each question have four level of measurement 0,1, 2 and 3, represent past week experiences. 0 means not applicable to person, 1 means applicable to some degree or sometime, 2 means applicable to considerable degree or good part of time, 3 means applicable to person very much or most of the time. Each question is separate for Stress(s), Anxiety (a) and Depression (d).

Nomi Waqas Gul

Principal Investigator

Indus Hospital

The sample size calculated was 30 samples per group. After adjusting error in non-response of data collection 50 samples will be drown from each group. Total 100 caregivers along with their children will be selected.

The patients will receive the same molecules (cetuximab and LEE011) but this phase I study will determine the DLTs by dose escalation of LEE011 (400 mg and 600mg).

Squamous Cell Carcinoma of the Head and Neck

The first 12 patients will receive cetuximab associated with LEE011 at doses of 400 mg and 600 mg daily to determine the DLTs and safety.
In the expansion part, besides safety, objective response rate, progression-free survival and overall survival will be calculated with the inclusion of 14 patients.

retinoblastoma/диария

Effect of Nurse-led Education on Parent's Anxiety and Depression on Managing Side Effects of Chemotherapy

Study of LEE011plus Cetuximab in Patients With a Cancer of the Head and Neck

Най-пълната база данни за лечебни билки, подкрепена от науката