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9 резултата
Dietary supplement enhancing the muscular energy metabolism, comprising an alkanoyl carnitine and ribose
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BACKGROUND OF THE INVENTION
The present invention relates to a health food/dietary supplement comprising as its characterising ingredients an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine and propionyl L-carnitine or their pharmacologically acceptable salts or
Dietary supplement enhancing the muscular energy metabolism, comprising an alkanoyl carnitine and ribose
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BACKGROUND OF THE INVENTION
The present invention relates to a health food/dietary supplement comprising as its characterising ingredients an alkanoyl L-carnitine selected from the group consisting of isovaleryl L-carnitine and propionyl L-carnitine or their pharmacologically acceptable salts or
Methods and compositions for inhibiting progression to chronic cardiac failure
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FIELD OF THE INVENTION
This invention relates generally to compositions and methods for reducing progression to heart failure as a consequence of cardiac stress.
BACKGROUND OF THE INVENTION
Without limiting the scope of the invention, its background is described in connection with the existing
Small molecule inhibitors of PARP activity
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BACKGROUND OF THE INVENTION
Poly ADP-ribose synthetase 1 (or PARP-1) is a dimeric nuclear protein, with two 113 kDa polypeptide subunits, each consisting of three functional domains: the DNA binding amino terminal domain with two zinc fingers for recognition of single and double strand DNA breaks,
Pharmaceutically acceptable salts of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide
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BACKGROUND OF THE INVENTION
The present invention relates to pharmaceutically acceptable salts of an amide substituted indazole which are inhibitors of the enzyme poly(ADP-ribose)polymerase (PARP), previously known as poly(ADP-ribose)synthase and poly(ADP-ribosyl)transferase. The compounds of the
Isoquinoline compounds and medicinal use thereof
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This application is a 371 of PCT/JP03/14904 filed Nov. 21, 2003.
TECHNICAL FIELD
The present invention relates to a novel isoquinoline compound and a pharmaceutical agent containing same as an active ingredient.
BACKGROUND ART
Poly(ADP-ribose)polymerase, hereinafter to be abbreviated as "PARP", is
Isoquinoline compound and pharmaceutical use thereof
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Вход / Регистрация
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a novel isoquinoline compound and a pharmaceutical agent containing same as an active ingredient.
BACKGROUND ART
Poly(ADP-ribose)polymerase, hereinafter sometimes to be abbreviated as "PARP", is an intranuclear enzyme that utilizes
Isoquinoline compound and pharmaceutical use thereof
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Вход / Регистрация
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a novel isoquinoline compound and a pharmaceutical agent containing same as an active ingredient.
BACKGROUND ART
Poly(ADP-ribose)polymerase, hereinafter sometimes to be abbreviated as "PARP", is an intranuclear enzyme that utilizes
Isoquinoline compound and pharmaceutical use thereof
Само регистрирани потребители могат да превеждат статии
Вход / Регистрация
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a novel isoquinoline compound and a pharmaceutical agent containing same as an active ingredient.
BACKGROUND ART
Poly(ADP-ribose)polymerase, hereinafter sometimes to be abbreviated as "PARP", is an intranuclear enzyme that utilizes
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