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15 резултата
Treatment of pulmonary disease with protease inhibitors
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FIELD OF THE INVENTION
The present invention relates to compositions and methods of treating pulmonary abnormalities such as adult respiratory distress syndrome (ARDS), neonatal respiratory distress syndrome (RDS), and/or sepsis syndrome, and the prevention thereof. More particularly, the invention
Therapeutic application of Kazal-type serine protease inhibitors
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This is a national stage entry of PCT/EP2008/001009, filed Feb. 11, 2008, which claims priority to EP 07002903.8, filed Feb. 12, 2007, all of which are incorporated herein by reference.
The subject of the present invention is, in the most general aspect, the therapeutic application of the Kazal-type
Interleukin-1 beta converting enzyme like apoptotic protease-6
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FIELD OF INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of
Interleukin-1.beta. converting enzyme like apoptotic protease-6
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FIELD OF INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of
Interleukin-1.beta. converting enzyme like apoptotic protease-6
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Вход / Регистрация
FIELD OF INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of
Interleukin-1 beta converting enzyme like apoptotic protease-7
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BACKGROUND OF THE INVENTION
Apoptosis, or programmed cell death (PCD), is a genetically regulated mechanism with a central role in both metazoan development and homeostasis. (Raff, 1992; Steller, 1995). The cell death machinery is conserved throughout evolution (Vaux et al., 1994) and is composed of
Interleukin-1 .beta. converting enzyme like apoptotic protease-6
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FIELD OF INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists of
Methods and compositions for inhibiting apoptosis using serine protease inhibitors
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1. FIELD OF THE INVENTION
The present invention relates to compositions and methods useful in the inhibition of apoptosis. Likewise, the present invention relates to methods of treating diseases associated with excessive or unregulated apoptosis.
2. BACKGROUND OF THE INVENTION
Normal development,
Modified MT-SP1 proteases that inhibit complement activation
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INCORPORATION BY REFERENCE OF SEQUENCE LISTING PROVIDED ELECTRONICALLY
An electronic version of the Sequence Listing is filed herewith, the contents of which are incorporated by reference in their entirety. The electronic file was created on May 9, 2014, is 2,308 kilobytes in size, and titled
Medicament for preventing and treating pseudomonas aeruginosa infections and method of its preparation
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The present invention relates to a human .gamma.-globulin preparation used for prevention and treatment of diseases caused by infection with P. aeruginosa as well as to a process of producing the gamma globulin preparation.
P. aeruginosa has brought forward various problems in the medical field as a
Apparatus for the extracorporeal treatment of blood
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims priority from European Patent Application No. 13197790.2, filed on Dec. 17, 2013, the contents of this application are hereby incorporated by reference in its entirety.
BACKGROUND OF THE INVENTION
State-of-the-art hospital treatment for
Endotoxin analysis
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FIELD OF THE INVENTION
The present invention relates to the field of endotoxin analysis
BACKGROUND OF THE INVENTION
Endotoxin Analysis
Endotoxins are lipopolysaccharides (LPS) found in the outer membrane of the cell-wall of Gram-negative bacteria. Endotoxins comprise a lipid part, called lipid A, a
Method for treatment and prevention of physiological shock
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FIELD OF THE INVENTION
The present invention is a method for the prevention and treatment physiologic shock involving the inhibition or removal of proteases in the small intestine and in circulation to prevent the generation of the mediators of shock. It is also a method for the identification of
4H-3,1-benzoxazin-4-one derivative
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TECHNICAL FIELD
The present invention relates to a novel 4H-3,1-benzoxazin-4-one derivative and, more particularly, to 4H-3,1-benzoxazin-4-one derivatives having a serine protease inhibiting effect.
BACKGROUND ART
Proteases (proteolytic enzymes) present in a living body play a role in the
Methods and compositions for treating diabetes
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1. FIELD OF THE INVENTION
The present invention relates to compositions and methods useful in the inhibition of apoptosis. Likewise, the present invention relates to methods of treating diseases associated with excessive or unregulated apoptosis.
2. BACKGROUND OF THE INVENTION
Normal development,
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