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FIELD OF THE INVENTION
The present invention relates to methods of treating pathogenic infection in mammals.
BACKGROUND OF THE INVENTION
About two billion people are thought to be infected with the bacillus Mycobacterium tuberculosis ("Mtb"), the causative agent of tuberculosis ("TB"). The majority
FIELD OF THE INVENTION
The present invention is directed to methods and compounds for inhibiting bacterial growth and treating a bacterial infection in a subject.
BACKGROUND OF THE INVENTION
When Metchnikoff discovered phagocytosis, he speculated that macrophages kill most ingested microbes by
FIELD OF THE INVENTION
The present invention relates to compositions and methods for inhibition of bacterial infections comprising Gram negative, Gram positive, and acid fast bacilli in general and mycobacterium tuberculosis (TB), mycobacterium avium complex (MAC), and anthrax in particular, as well
FIELD OF INVENTION
The invention relates to methods of treating Mycobacterium tuberculosis infections.
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy,
TECHNICAL FIELD
The invention relates to the field of recombinant DNA and viral vector vaccines. Specifically, it relates to recombinant DNA and viral vectors harboring nucleic acids encoding multiple antigens and/or adjuvants.
BACKGROUND
Tuberculosis (TB) has been a major worldwide threat to human
JOINT RESEARCH AGREEMENT
The claimed invention was made by or on behalf of the following parties to a joint research agreement: Crucell Holland B.V. and Aeras Global TB Vaccine Foundation. The agreement was in effect on or before the date the claimed invention was made, and the claimed invention was
FIELD OF THE INVENTION
The invention relates to the field of recombinant DNA and viral vector vaccines. Specifically, it relates to recombinant DNA and viral vectors harboring nucleic acids encoding multiple antigens and/or adjuvants.
BACKGROUND OF THE INVENTION
Tuberculosis (TB) has been a major
BACKGROUND OF THE INVENTION
Vaccines containing various living avirulent cells of tubercle bacilli, in particular Bacillus Calmette-Guerin (BCG), an attenuated bovine tuberculosis organism (Mycobacterium bovis), have been used to induce immunity against acquired tuberculosis disease in man.
FIELD OF THE INVENTION
The present invention relates to compositions and methods for inhibition of bacterial infections comprising Gram negative, Gram positive, and acid fast bacilli in general and mycobacterium tuberculosis (TB), mycobacterium avium complex (MAC), and anthrax in particular, as well
FIELD OF THE INVENTION
The present invention relates to compositions and methods for inhibition of bacterial infections comprising Gram negative, Gram positive, and acid fast bacilli in general and mycobacterium tuberculosis (TB), mycobacterium avium complex (MAC), and anthrax in particular, as well