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urinary incontinence/възпаление

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Pharmaceutical composition for preventing / treating TRPV1 activity-related and inflammation-related diseases or conditions containing maillard peptide separated from well-aged traditional soy sauce as active ingredient

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is a 371 of PCT/KR2010/007845, filed Nov. 8, 2010, which claims the benefit of Korean Patent Application No. 10-2009-0106912, filed Nov. 6, 2009, the entire contents of each of which are incorporated herein by reference. TECHNICAL FIELD The

Hydroxy-tetrahydro-naphthalenylurea derivatives

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DETAILED DESCRIPTION OF INVENTION Technical Field The present invention relates to a hydroxy-tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The hydroxy-tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR1)

Antagonists of the vanilloid receptor subtype 1 (VR1) and uses thereof

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FIELD OF INVENTION The present invention relates to spirochromane compounds of formula (I), which are useful for treating disorders caused by or exacerbated by vanilloid receptor type 1 (VR1) activity. The present invention also includes pharmaceutical compositions containing compounds of formula

Antagonists of the vanilloid receptor subtype 1 (VR1) and uses thereof

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FIELD OF INVENTION The present invention relates to spirochromane compounds of formula (I), which are useful for treating disorders caused by or exacerbated by vanilloid receptor type 1 (VR1) activity. The present invention also includes pharmaceutical compositions containing compounds of formula

Tetrahydro-quinolinylurea derivatives

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This application is a 371 of PCT/EP2004/012051, filed Oct. 26, 2004. DETAILED DESCRIPTION OF INVENTION 1. Technical Field The present invention relates to a tetrahydro-quinolinylurea derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-quinolinylurea

Transdermal delivery of medicaments with combinations of cetylated fatty ester penetrant complexes

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates in general to the field of transdermal and dermal drug delivery by using formulations of said compositions including chemical penetrants molecules, polar solvents, cream base, antioxidants and therapeutic

Benzoamide piperidine containing compounds and related compounds

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The present invention relates to certain benzoamide piperidine containing compounds and related compounds that exhibit activity as NK-1 receptor antagonists, (e.g., substance P receptor antagonists), to pharmaceutical compositions containing them, and to their use in the treatment and prevention of

Hydroxy tetrahydro-naphthalenylurea derivatives

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TECHNICAL FIELD The present invention relates to hydroxy-tetrahydro-naphthalenylurea derivatives which are useful as an active ingredient of pharmaceutical preparations. The hydroxy-tetrahydro-naphthalenylurea derivatives of the present invention has vanilloid receptor (VR) antagonistic activity,

Tetrahydro-naphthalene derivatives

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DETAILED DESCRIPTION OF INVENTION 1. Technical Field The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR) antagonistic

Tetrahydro-naphthalene derivatives

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DETAILED DESCRIPTION OF THE INVENTION 1. Technical Field The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR)

Tetrahydro-naphthalene derivatives

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DETAILED DESCRIPTION OF INVENTION 1. Technical Field The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR) antagonistic

Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor

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TECHNICAL BACKGROUND The present invention relates to compounds of formula (I), which are useful for treating disorders caused by exacerbated by or vanilloid receptor activity, pharmaceutical compositions containing compounds of formula (I) and are useful in treating pain, bladder overactivity, and

Quinine compounds, and optical isomers, preparation method and medical use thereof

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CROSS-REFERENCE TO RELATED APPLICATION This application is the U.S. national phase of PCT Appln. No. PCT/CN2014/000669 filed Jul. 11, 2014, which claims priority to Chinese application 201310297901.7 filed Jul. 13, 2013, the disclosures of which are incorporated in their entirety by reference

Methods for making central nervous system agents that are TRPV1 antagonists

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TECHNICAL BACKGROUND The present invention relates to methods of making compounds that are useful for treating disorders caused by or exacerbated by vanilloid receptor activity, such as pain, bladder overactivity, and urinary incontinence. BACKGROUND OF INVENTION Nociceptors are primary sensory

Therapeutic agents useful for treating pain

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1. FIELD OF THE INVENTION The present invention relates to Cyanoiminopiperazine Compounds, compositions comprising an effective amount of a Cyanoiminopiperazine Compound and methods for treating or preventing pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD),
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