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Страница 1 от 46 резултата
Toxic uveitis caused by pharmacodynamic interactions of Rifabutin and protease inhibitors: a case report.
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Вход / Регистрация
Toxic reactions (uveitis, arthritis and leucopenia) of Rifabutin at normal doses should always be considered because of pharmacokinetic interactions with other drugs (e.g. the protease inhibitors). This case demonstrates that this kind of uveitis is clinically significant as the diagnosis of
Expression of serine protease inhibitor 3 in ocular tissues in endotoxin-induced uveitis in rat.
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OBJECTIVE
To ascribe the serine protease inhibitor 3 (SPI-3) as an ocular acute inflammatory molecule and to clarify its producing cells in an endotoxin-induced uveitis (EIU) model.
METHODS
Male Wistar rats were injected with lipopolysaccharide (LPS), and the expression of SPI-3 mRNA in the ocular
[Use of the protease inhibitor kontrikal in treating phakogenic uveitis].
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Uveitis following administration of the protease inhibitor indinavir to a patient with AIDS.
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Drug-induced uveitis in aids patients: two case reports.
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Вход / Регистрация
Patients with acquired immunodeficiency syndrome (AIDS) can develop severe uveitis. Although infectious and autoimmune causes must always be considered, drug induced uveitis is also an important etiology. Herein, we present two case reports illustrating the classical presentation of rifabutin and
Cicatrization of cytomegalovirus retinitis following introduction of highly active anti-retroviral therapy: uveitis as a possible indicator of good ocular prognosis.
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OBJECTIVE
To quantify the inflammatory reaction that can be seen in HIV-infected patients with cytomegalovirus (CMV) retinitis after the introduction of an HIV protease inhibitor and correlate it with ocular findings and systemic HIV parameters.
METHODS
Report of a patient with CMV retinitis
[Acute hypopyon uveitis with rifabutin therapy of systemic Mycobacterium avium complex (MAC) infection in AIDS].
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BACKGROUND
Hypopyon-uveitis has been identified as a dosage-dependent side effect in patients with acquired immunodeficiency syndrome who are treated for Mycobacterium avium complex (MAC) infection with systemic rifabutin.
METHODS
We report a 38-year-old female AIDS patient with bilateral hypopyon
Alpha 1-antitrypsin in acute anterior uveitis and rheumatic diseases.
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To test the pathogenetic role of the phenotype MZ of alpha 1-antitrypsin/alpha 1-protease inhibitor (PI) in acute anterior uveitis (AAU) and in different rheumatic diseases we examined 360 unrelated patients including 93 with AAU alone, 24 patients with AAU and ankylosing spondylitis (AS), 21
Uveitis in patients treated with intravenous cidofovir.
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OBJECTIVE
To study the characteristics of uveitis occurring during intravenous cidofovir treatment for CMV retinitis in patients with AIDS.
METHODS
We retrospectively studied ten cases (16 eyes) of uveitis in patients with CMV retinitis treated with intravenous cidofovir. All the patients had
Alpha 1-antitrypsin and acute anterior uveitis.
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To test the pathogenetic role of the phenotype MZ of alpha 1-antitrypsin/alpha 1-protease inhibitor (PI) in acute anterior uveitis (AAU), 156 patients with AAU were examined. Sera of all patients and 120 healthy controls were PI-typed using isoelectric focusing. There were no significant differences
Bilateral uveitis associated with concurrent administration of rifabutin and nelfinavir.
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Вход / Регистрация
Rifabutin-associated uveitis has been recognized as a dosage-dependent side effect. Previous studies have reported that clarithromycin or fluconazole may elevate concentrations of rifabutin through inhibition of metabolism through the cytochrome P-450 pathway. Nelfinavir is a protease inhibitor
[Effect of kontrikal on the course of experimental nonspecific phacogenic uveitis].
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Nonspecific phacogenic uveitis (NPGU) was simulated in 21 chinchilla rabbits to follow the time course of the blood serum proteolytic activity and the principal protease inhibitors (alpha 1 inhibitor and alpha 2 macroglobulin) in various stages of the inflammatory process. Effects of contrykal, a
Genetic background of acute anterior uveitis.
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To determine the hereditary pattern of acute anterior uveitis, we examined seven families-one family with four cases, one family with three cases, and four families with two cases of acute anterior uveitis. A total of 16 patients with uveitis and 28 relatives underwent ocular examinations and
Structure-function studies of S-antigen: use of proteases to reveal a dominant uveitogenic site.
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Retinal S-antigen induced experimental autoimmune uveitis (EAU) is a severe, predominantly T-cell mediated inflammatory disease of the uveal tract and retina of the eye. Pretreatment of LEW rats with the monoclonal antibody, MAbS2.4.C5, which defines an epitope in S-antigen, has been shown to
Increased matrix metalloproteinases in the aqueous humor of patients and experimental animals with uveitis.
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OBJECTIVE
Matrix metalloproteinases (MMPs) play a major role in connective tissue remodelling, wound healing and embryogenesis. They have also been implicated in pathological tissue degradation in diseases such as rheumatoid arthritis (RA), osteoarthritis (OA), and tumor invasion. The aim of this
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