vulvar neoplasms/никотин

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Current etiopathogenetic views in vulvar cancer.

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We considered 59 patients, from 19 to 79 years, treated for vulvar neoplastic pathology (32 of 59 had multiple squamous neoplasias of the anogenital region). It appeared that vulvar cancer is a disease of aged women and in particular between sixty and seventy years, while it isn't common under the

CYP2D6 genotype and the incidence of anal and vulvar cancer.

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The risks of anal and vulvar cancer are strongly related to cigarette smoking. Smokers are exposed to a substantial quantity of tobacco-specific nitrosamines, including 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). NNK is present in the mucus of the female genital tract. The enzyme

Vulvar cancer in young women: demographic features and outcome evaluation.

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OBJECTIVE The objective of the study was to identify prognostic and environmental factors associated with vulvar carcinoma in young women. METHODS This study was a review of patients younger than 45 years who were diagnosed with vulvar squamous cell carcinoma between 1994 and 2006. RESULTS Fifty-six

[Current epidemiology of vulvar cancer].

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Cancer of the vulva is a rare disease accounting for only 3 to 5% of all gynaecologic cancers. The incidence rates of this cancer vary depending upon the country considered, the lowest rates being reported for Asian and African populations. An increased incidence of in situ carcinomas of the vulva

Cancer in Chiang Mai, North Thailand. A relative frequency study.

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The relative frequency of histologically diagnosed cancer at the Chiang Mai Medical School in North Thailand in 1964-67 inclusive is examined.Most of the 1877 cancers seen are in Thais (males, 927; females, 908), the remainder arising in Chinese (males, 21; females, 12), Hill People (males, 6;

Vulvar intraepithelial neoplasia III: occult cancer and the impact of margin status on recurrence.

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OBJECTIVE To determine the impact of margin status on disease recurrence and the incidence of occult cancer in women diagnosed with vulvar intraepithelial neoplasia (VIN) III and treated with surgical excision. METHODS Between 1989 and 1995, 73 women were diagnosed preoperatively with VIN III by

Clinical and histologic features of vulvar carcinomas analyzed for human papillomavirus status: evidence that squamous cell carcinoma of the vulva has more than one etiology.

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The association between the human papillomavirus (HPV) and malignant neoplasms of the uterine cervix is well established; however, its role in the pathogenesis of vulvar cancer has not been well defined. This study correlates the clinical and histopathologic features of 21 invasive carcinomas of the

Therapy for Primary Vulvar Carcinoma.

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The rather rare vulvar cancer is almost always a squamous cell carcinoma that mostly develops from an underlying VIN or HPV infection. In addition, lichen sclerosus et atrophicans, immune deficiency, nicotine abuse or anogenital intraepithelial neoplasias may play a role in the pathogenesis.

Case of lung carcinoma revealed by vulvar metastasis associated with systemic scleroderma and literature review.

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Metastatic carcinoma to the vulva is rare, where the incidence is believed to be between 5% and 8%. However, malignant tumors have been described in 3-11% of systemic scleroderma (SSc) cases. We report the case of one patient, a 66-year-old postmenopausal woman, whose medical history was marked with

The effect of sartorius transposition on wound morbidity following inguinal-femoral lymphadenectomy.

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In spite of efforts to reduce complications associated with inguinal-femoral lymphadenectomy (IFL), morbidity continues to be substantial. We sought to assess the efficacy of sartorius transposition (ST) in reducing groin wound complications following IFL, in patients with vulvar malignancy. The

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