Herbal Medicines for Gastrointestinal Disorders in Children and Adolescents: A Systematic Review.
Ključne riječi
Sažetak
BACKGROUND
Gastrointestinal disorders are common childhood complaints. Particular types of complementary and alternative medicine, such as herbal medicine, are commonly used among children. Research information on efficacy, safety, or dosage forms is still lacking.
OBJECTIVE
To systematically summarize effectiveness and safety of different herbal treatment options for gastrointestinal disorders in children.
METHODS
Medline/PubMed, Scopus, and the Cochrane Library were searched through July 15, 2016.
METHODS
Randomized controlled trials comparing herbal therapy with no treatment, placebo, or any pharmaceutical medication in children and adolescents (aged 0-18 years) with gastrointestinal disorders were eligible.
METHODS
Two authors extracted data on study design, patients, interventions, control interventions, results, adverse events, and risk of bias.
RESULTS
Fourteen trials with 1927 participants suffering from different acute and functional gastrointestinal disorders were included in this review. Promising evidence for effectiveness was found for Potentilla erecta, carob bean juice, and an herbal compound preparation including Matricaria chamomilla in treating diarrhea. Moreover, evidence was found for peppermint oil in decreasing duration, frequency, and severity of pain in children suffering from undifferentiated functional abdominal pain. Furthermore, evidence for effectiveness was found for different fennel preparations (eg, oil, tea, herbal compound) in treating children with infantile colic. No serious adverse events were reported.
CONCLUSIONS
Few studies on specific indications, single herbs, or herbal preparations could be identified.
CONCLUSIONS
Because of the limited number of studies, results have to be interpreted carefully. To underpin evidence outlined in this review, more rigorous clinical trials are needed.
