Zhongguo zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban 2000-Jan

[Treatment of bacterial peritonitis with dachengqi decoction and rhubarb in mice].

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P Hu

F Bai

D Li

ČLANAK: 11783340

BioSeek: 11783340

Ključne riječi

bakterijemija

peritonitis

rabarbara

antibakterijski

antibiotik

antiseptik

Sažetak

OBJECTIVE

To observe the antiseptic effect of Dachengqi Decoction (DCQD) or rhubarb, one of the ingredients of DCQD in mice.

METHODS

The model mice were established by peritoneal injection of Escherichia coli (10(8)/ml) or Proteus vulgaris (10(6)/ml) respectively. DCQD or rhubarb was given from 2 days before to 2 days after modelling for preventing and treating.

RESULTS

The mortality and bacteremia occurrence of the treatment group were significantly lower than those of the control group (P < 0.05). Both DCQD and rhubarb showed protective effect on Escherichia. coli or Proteus vulgaris infection in mice. The cardiac blood smear and culture of survival mice in prevention plus treatment group and model group showed negative (bacteria) results but those of dead mice showed positive result.

CONCLUSIONS

DCQD and rhubarb have excellent bactericidal effect.