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aesculus/antimikotično
Veza se sprema u međuspremnik
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Molecular Mechanism for Cellular Response to β-Escin and Its Therapeutic Implications.
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β-escin is a mixture of triterpene saponins isolated from the horse chestnut seeds (Aesculus hippocastanum L.). The anti-edematous, anti-inflammatory and venotonic properties of β-escin have been the most extensively clinically investigated effects of this plant-based drug and randomized controlled
Pavietin, a coumarin from Aesculus pavia with antifungal activity.
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A new prenylated coumarin, S-6-[2-(hydroxymethyl)butoxy]-7-hydroxy-4-methyl-2 H-chromen-2-one ( 1), named pavietin, has been isolated from the leaves of an Aesculus pavia genotype along with three known flavonol glycosides, quercetin 3- O-alpha-rhamnoside (quercitrin, 2), quercetin 3-
Aescin: pharmacology, pharmacokinetics and therapeutic profile.
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Aescin, the major active principle from Aesculus hippocastanum (Hippocastanaceae) the horse chestnut tree, has shown satisfactory evidence for a clinically significant activity in chronic venous insufficiency (CVI), haemorrhoids and post-operative oedema. In one controlled trial aescin was shown to
Rational therapy of chronic venous insufficiency--chances and limits of the therapeutic use of horse-chestnut seeds extract.
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METHODS
We report two clinical studies, one already published, performed in patients with early and advanced chronic venous insufficiency (CVI). In both, compression therapy and oral therapy with horse-chestnut seeds extracts (HCSE) were compared to placebo.
RESULTS
The published study in early CVI
Sodium beta-aescin may be an effective therapeutic agent for Bell's palsy.
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Although Bell's palsy is the most common acute facial paralysis, the cause of it is still unknown. This made the treatment for it remain very limited. Many methods are simply symptomatic treatment. Up to now we have known that Bell's palsy is related to viral infection and the pathomechanism of
A review of the microcirculation in skin in patients with chronic venous insufficiency: the problem and the evidence available for therapeutic options.
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Impairment of the cutaneous microcirculation is a major predisposing factor in inflammation and ulceration in patients with chronic venous insufficiency (CVI). Increase of capillary filtration rate predisposes to the formation of edema. Local lymphedema is a complication of CVI, often
Plant extracts inhibit ADP-induced platelet activation in humans: their potential therapeutic role as ADP antagonists.
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Adenosine diphosphate (ADP) plays a pivotal role in platelet activation. Platelet hyperactivity is associated with vascular disease and also has a key role in haemostasis and thrombosis. ADP activates platelets through three purinoceptor subtypes, the G(q)-coupled P2Y(1) receptor, G(i)-coupled
[Therapeutic properties of Aesculus hippocastanum].
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[The active therapeutic principle of horse chestnut (Aesculus hippocastanum). Part 1. Classification of the active substance].
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[The active therapeutic principle of horse chestnut (Aesculus hippocastanum). Part 4. On the toxicology of the active principle].
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[The active therapeutic principle of horse chestnut (Aesculus hippocastanum). Part 2. On the chemistry of the active substance].
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[Therapeutic effects of a horse-chestnut ointment].
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[The therapeutic effects of Aesculus hippocastanum extract].
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[Therapeutic use of extracts of horse chestnuts in rheumatism].
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[Horse chestnut inhibits lysosomal enzyme activity--therapeutic success in varicose veins].
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