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angioedema/kalij

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Angioneurotic edema attributed to the use of losartan.

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BACKGROUND Angioedema is a well-known adverse effect of angiotensin-converting enzyme inhibitors. The bradykinin accumulation as a result of the decreased degradation of bradykinin is thought to be the causal mechanism. Angiotensin II antagonists seem to have no effect on the degradation of
Angioedema in the mouth or upper airways is a feared adverse reaction to angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blocker (ARB) treatment, which is used for hypertension, heart failure and diabetes complications. This candidate gene and genome-wide association study
BACKGROUND Losartan potassium, an orally active, highly selective AT1 angiotensin II receptor inhibitor, effectively reduces blood pressure by direct receptor blockade, thereby lessening the likelihood of angiotensin converting enzyme (ACE) inhibitor-associated side effects such as dry cough or

Potassium iodide sensitivity in four patients with hypocomplementemic vasculitis.

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During metabolism studies of radiolabeled proteins in 126 participants four patients were suspected of being sensitive to potassium iodide (Kl) because they repeatedly developed urticaria and other symptoms after Kl administration. Two of the four patients suspected of Kl sensitivity and 10 control

Angioedema associated with angiotensin II receptor antagonists: challenging our knowledge of angioedema and its etiology.

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BACKGROUND Use of angiotensin converting enzyme inhibitors has long been associated with angioedema. Increased levels of bradykinin caused by the inhibition of angiotensin converting enzyme have been thought to be responsible for this side effect. Angiotensin II receptor antagonists (AT2 blockers),

A risk-benefit assessment of losartan potassium in the treatment of hypertension.

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Losartan potassium is the first of a new class of orally active antihypertensive drugs which antagonise the action of angiotensin (AT) II at the AT1 receptor subtype. Losartan potassium is converted by the liver to the active metabolite E-3174, which is a more potent antagonist at the AT1 receptor.

[Drug-interactions and adverse effects of losartan potassium, an angiotensin II receptor antagonist].

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Losartan potassium is mainly metabolized by P450 chiefly in the liver. A P450 inducer, phenobarbital, has no significant effects on the pharmacokinetics of losartan. Cimetidine, known to inhibit P450 activity, has no remarkable effects on the metabolism of losartan. Side effects of losartan has been

Epidemiology, pathophysiology, prognosis, and treatment of systolic and diastolic heart failure in elderly patients.

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American College of Cardiology/American Heart Association class I recommendations for treating patients with heart failure (HF) and abnormal left ventricular ejection fraction are diuretics in patients with fluid retention, an angiotensin-converting enzyme (ACE) inhibitor unless contraindicated, a

Treatment of heart failure with decreased left ventricular ejection fraction.

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Class I recommendations for treating patients with current or prior symptoms of heart failure with reduced left ventricular ejection fraction (LVEF) include using diuretics and salt restriction in individuals with fluid retention. Use angiotensin-converting enzyme (ACE) inhibitors, beta blockers,

Renin inhibitors.

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KEY POINTS AND PRACTICAL RECOMMENDATIONS: • Aliskiren, the sole oral renin inhibitor approved by the US Food and Drug Administration, is indicated for the treatment of hypertension, either as monotherapy or in combination, with reductions in blood pressure similar to other agents. • Early evidence

Converting enzyme inhibitors in the treatment of hypertension.

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The renin-angiotensin system has a wide range of physiological actions, and thus interference with the system has attractive therapeutic potential. The orally active angiotensin converting enzyme (ACE) inhibitors have so far been the most successful drugs in this area. They lower arterial pressure

Inpatient Initiation of Sacubitril/Valsartan

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Objective: Discuss the literature and describe strategies to overcome barriers of inpatient initiation of sacubitril/valsartan in patients with heart failure with reduced ejection fraction (HFrEF). Data Sources: A PubMed, EMBASE, and Google Scholar literature search (January 2014 to

Losartan: first of a new class of angiotensin antagonists for the management of hypertension.

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Angiotensin receptor antagonists represent a new class of drugs for the treatment of patients with hypertension. Reduction of blood pressure in patients with essential hypertension requires increased activity of the renin-angiotensin system. Losartan, the first orally active, nonpeptide angiotensin

Angiotensin converting enzyme inhibitors in hypertension: potential problems.

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OBJECTIVE To review potential problems associated with the use of angiotensin converting enzyme (ACE) inhibitors in the treatment of patients with hypertension. UNASSIGNED ACE inhibitors cause a drop in blood pressure depending on the circulating level of angiotensin II. This may be a problem in

[Anaphylaxis caused by royal jelly].

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Royal jelly is the food on which are fed and which causes them to develop into queen bees. It is claimed to have rejuvenating virtues for human beings. This report describes a 15-year-old atopic woman who presented, 15 minutes after the intake of royal jelly, local angioedema, generalised urticaria,
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