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antiplatelet/gojaznost

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Common Limb Length in One-anastomosis Gastric Bypass

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The present study is a prospective, randomized comparative clinical trial involving 60 patients (due to limited flow rate and high expenses [14]) who will be subjected to laparoscopic single anastomosis gastric bypass at the department of surgery, Mansoura university, Mansoura, Egypt at the period

Effect of Rosuvastatin on the Clinical Features of Preeclampsia

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Preeclampsia is a multisystem disorder that complicates 3-5% of pregnancies and remains a major cause of maternal, fetal, and neonatal morbidity and mortality.(1) Preeclampsia is characterized by the development of new onset hypertension (HTN) and the establishment of proteinuria. Other signs and

Prospective Cohort Study on Minimal Invasive Coronary Surgery

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1. MIDCAB procedure introduction 1. Surgery preparation: General anesthesia, double lumen tracheal intubation. In the supine position, tilt 15° to the right. An automatic defibrillation electrode is attached to the right front and left rear chest wall, and the external defibrillator is connected. A

Triple Antithrombotic Therapy in Cardiac Patients Requiring Revascularization

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Atrial fibrillation (AF) is the most common arrythmia in clinical practice that often requires stroke prevention with an anticoagulant. Oral anticoagulation (OAC) with either warfarin or non-vitamin K oral anticoagulants (NOACs) significantly decreases the incidence of ischemic stroke and peripheral

Risk Prediction of Venous Thromboembolism in Critically Ill

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OVERALL STUDY OBJECTIVES 1. To develop and internally validate a risk assessment model for predicting the risk of in-hospital VTE in critically ill patients (phase 1) 2. To externally validate this new model (phase 2) 3. To compare the performance of this model to other VTE prediction models

Use of Platelet Indices for Prediction of Recurrent Miscarriage

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- Study population: - Sample size: This study will be conducted on (70) women attending outpatient clinic divided into two groups: - 1st Group (35): women with history of recurrent miscarriage (two or more consecutive miscarriages) - 2nd Group (35): women without history of recurrent miscarriage and

Surviving a Decade or More After Coronary Revascularization in a Middle Eastern Population

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Middle Eastern patients aged 18 years or above presenting to cardiology service at one tertiary care center who had coronary revascularization (stent or coronary bypass surgery, i.e., index procedure) at least 10 years back, will interviewed to determine: 1. Evolution of cardiovascular risk factors

IRELAnD: Investigating the Role of Early Low-dose Aspirin in Diabetes

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Pregestational diabetes represents a high-risk for evolution of preeclampsia (PET), with rates of PET within this group at approximately 20%. The combination of diabetes and preeclampsia places the pregnancy at heightened risk for hypoxia and stillbirth. Placental dysfunction, due to disordered

The Procedural Success and Complication Rate of the Left Distal Radial Approach

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Femoral artery has been traditionally used as a standard route for coronary angiography (CAG) and percutaneous coronary intervention (PCI). Recently, the frequency of use of transradial approach (TRA) is increasing. TRA has several advantages in terms of more comfortable feeling, immediate

Does the Human Gut Microbiome Serve as a Novel Personalized Therapeutic Target for Coronary Atherosclerosis?

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Introduction: The human gastrointestinal system is populated with a variety of symbiotic microorganisms, namely microbiota. Its total weight is approximately 2 kilograms, containing trillions of microorganisms. The microbiome is the total genetic (metagenomic) data of the microbiota. In recent

Influence of Exercise Training on Platelet Aggregability in a Post-myocardial Infarction Population

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1. Introduction: Platelet reactivity is closely involved in the pathophysiology of acute coronary syndromes (ACS). However, despite the development of newer and more effective antiplatelet drugs (among other therapeutic interventions), the risk of ischemic events recurrence after an episode of ACS

Aspirin and Renal Disease Progression in Patients With Type 2 Diabetes

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Epidemiological data show that type 2 diabetes has an epidemic trend worldwide. The increase in food intake, the greater availability of refined grains and the reduction of physical activity had, in fact, negative effects in most areas. It is expected that the number of people suffering from

Role of Podocan and Wnt Pathway Regulatory Molecules in Coronary Artery Disease

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Smooth muscle cells (SMC's) critically influence the clinical course of vascular disease . The close regulation of SMC migration and proliferation within the intimal space is critical in maintaining a delicate balance between insufficient and excessive atherosclerotic plaque repair . When SMC

WilL LOWer Dose Aspirin be More Effective Following ACS? (WILLOW - ACS)

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Aspirin has an established role in the treatment of ACS and secondary prevention of ischaemic heart disease. In the landmark trial of aspirin in ACS, ISIS-2 (1988), it conferred a benefit of similar magnitude to thrombolysis. The addition of a second antiplatelet agent (a P2Y12 inhibitor) to aspirin

PRotective Effect on the Coronary Microcirculation of Patients With DIabetes by Clopidogrel or Ticagrelor

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Introduction: Patients with Diabetes Mellitus (DM) Type 2 still consistently perform worse than their non-diabetic counterparts especially in the setting of Percutaneous Coronary Intervention (PCI). The abnormal coronary microcirculation along with the higher risk of distal embolization of particles
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