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arteriosclerosis/gojaznost
Veza se sprema u međuspremnik
Page 1 od 85 rezultati
Smooth muscle growth inhibitory composition, diagnostic method for arteriosclerosis, and kit therefor
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TECHNICAL FIELD
This invention relates to a smooth muscle growth inhibitory composition comprising apM1 (adipose most abundant gene transcript 1) as an active ingredient, a method for diagnosis of arteriosclerosis (atherosclerosis) which comprises assaying said apM1 in a sample, and a diagnostic kit
Smooth muscle growth inhibitory composition, diagnostic method for arteriosclerosis, and kit therefor
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TECHNICAL FIELD
This invention relates to a smooth muscle growth inhibitory composition comprising apM1 (adipose most abundant gene transcript 1) as an active ingredient, a method for diagnosis of arteriosclerosis (atherosclerosis) which comprises assaying said apM1 in a sample, and a diagnostic kit
Method for combating obesity
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The present invention relates to a method for controlling obesity and diseases caused by obesity.
The peptide hormone endothelin is known for its strong vasoconstrictor properties. Endothelin receptor antagonists are therefore mainly being tested in cardiovascular pathologies.
The invention relates
Substances KF-1040 and process for producing of the same
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FIELD OF THE INVENTION
The present invention relates to novel KF-1040 substance having an inhibitory activity for lipid metabolism as well as to a process for producing such substance.
PRIOR ARTS
There have been known anti-obesity drugs and drugs for hyperlipidemia. For example, centrally acting
Pyrazolopyridine compound and processes for preparation thereof
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The present invention relates to novel pyrazolopyridine compound and a pharmaceutically acceptable salt thereof.
More particularly, it relates to novel pyrazolopyridine compound and a pharmaceutically acceptable salt thereof, which are adenosine antagonists and possess various pharmaceutical actions
2-heteroaryl-substituted benzimidazole derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is the National Stage of International Application No. PCT/JP2004/019843, filed 28 Dec. 2004, which claims the benefit of JP 2003-436992 filed in Japan on Dec. 29, 2003 and JP 2004-235696 filed in Japan on Aug. 13, 2004, priority of which is
Aryloxy-substituted benzimidazole derivatives
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TECHNICAL FIELD
The present invention relates to a glucokinase activator comprising, as the active ingredient thereof, an aryloxy-substituted benzimidazole derivative and useful in the field of medicines. Further, it relates to a novel aryloxy-substituted benzimidazole derivative.
BACKGROUND
Benzene compounds
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to benzene compounds, and more particularly, to novel benzene compounds having inhibition activity on acetyl CoA carboxylase ("ACC" hereinafter).
2. Discussion of the Background
It has become clear in recent years
25-hydroxyvitamin D3 24-hydroylase transgenic rats
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TECHNICAL FIELD
This invention relates to 25-hydroxyvitamin D.sub.3 24-hydroxylase transgenic animals.
BACKGROUND ART
The transgenic animal carries a gene introduced to its own or progenitor's germ cell line in an early stage of development (usually, single cells).
Wagner et al. (1981, ProNAS, USA,
Adiponectin promoter and use thereof
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TECHNICAL FIELD
The present invention relates to a promoter containing novel regulatory nucleotide sequences for gene expression and use thereof. Concretely, it relates to a DNA containing the promoter region with regulatory sequences of human adiponectin gene, transformants transformed with the
Application of D-psicose to suppression of abnormal circadian increase in blood glucose level
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TECHNICAL FIELD
The present invention relates to a technique for using D-psicose in suppressing the abnormal intra-day increase of plasma glucose concentration (blood glucose level). More specifically, the invention relates to the application of the action of D-psicose to suppress the abnormal
Compounds for the treatment of metabolic disorders
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BACKGROUND OF THE INVENTION
Diabetes mellitus is a major cause of morbidity and mortality. Chronically elevated blood glucose leads to debilitating complications: nephropathy, often necessitating dialysis or renal transplant; peripheral neuropathy; retinopathy leading to blindness; ulceration of the
Adipocyte differentiation inhibiting peptide and adipocyte differentiation inhibiting agent using the peptide as active component thereof
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TECHNICAL FIELD
This invention relates to a novel adipocyte differentiation inhibiting peptide, adipocyte differentiation inhibiting agent using the peptide as an active component thereof, a specific health food (so-called physiologically physiolosically functional food) possessing the function of
Pyripyropene derivatives having an ACAT2-inhibiting activity
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TECHNICAL FIELD
The present invention relates to pyripyropene A derivatives having an improved inhibitory activity against acyl-CoA cholesterol acyltransferase (hereinafter abbreviated as ACAT) isozyme 2 and more particularly it relates to such derivatives having substituted by 7-acyl or by
Heterocyclic compound and use thereof
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TECHNICAL FIELD
The present invention relates to a novel heterocyclic compound having superior properties as a pharmaceutical agent, a production method thereof and use thereof. More particularly, the present invention relates to a heterocyclic compound having a particular structure, which has an
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