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Ischemic heart disease is worldwide the single most frequent cause of death. The number of patients surviving acute myocardial injury is increasing due to improved acute treatment. However, after the initial repair, the tissue undergoes a remodeling phase to compensate for the damaged area. This
SAS is characterized by abnormality during sleep and hypoxemia from apnea and hypopnea, followed by systemic inflammation and organ dysfunction like cardiovascular diseases. Systemic inflammation causes the activation of arachidonic acid metabolism, producing prostaglandins (PGs) and leukotrienes
The value of anaemia therapy with recombinant erythropoietin and iron for improvement of cardiovascular outcome has been clearly demonstrated in dialysis patients and is standard of care. In this patient collective one study shows that correction of anaemia together with blood pressure control does