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Page 1 od 69 rezultati
Method of treating allergic asthma with antibodies to IL-6
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The sequence listing in the file named "56256o2006.txt" having a size of 332,224 bytes that was created Sep. 26, 2017 is hereby incorporated by reference in its entirety.
BACKGROUND OF THE INVENTION
Field of the Invention
This invention is an extension of Applicants' prior invention disclosed in the
Antiallergic spray preparations
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FIELD OF THE INVENTION
The present invention relates to preparations of zinc compounds for use in the treatment and/or prophylaxis of allergic conditions.
DISCUSSION OF THE ART
Zinc and its compounds have long been recognized as possessing certain therapeutic functions. Particularly well recognized
Thiazolo[3,2-a][1,2,3]triazolo[4,5-d]pyrimidine and [1,3,4]thiadiazolo[3,2-a][1,2,3]triazolo[4,5-d]pyrimidine derivatives
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FIELD OF THE INVENTION
This invention relates to triazolopyrimidine derivatives and physiologically acceptable salts thereof which are useful as anti-allergic agent.
BACKGROUND OF THE INVENTION
It is well known that a chemical mediator released by antigen-antibody reaction, e.g., histamine, plays an
Peptides derived fram complement peptide C3a sequence and antiallergic compositions comprising them
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FIELD OF THE INVENTION
The present invention is in the field of allergy and relates to peptides derived from the complement peptide C3a and to their use in the prevention and treatment of allergies.
BACKGROUND OF THE INVENTION
Mast cells and basophils play a central role in inflammatory and
Novel anthranilic acid derivatives
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to novel anthranilic acid derivatives exhibiting an extremely strong antiallergic activity when administered orally to mammals including human beings. More particularly, this invention relates to anthranilic acid
Substituted heteroaryl analogs of 4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
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BACKGROUND OF THE INVENTION
The present invention is novel compounds which are 4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidine substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical
Derivatives of 3-hydroxyazabenzo(beta)thiophene useful as 5-lipoxygenase inhibitors
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BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
Derivatives of 3-hydroxyazabenzo(B)thiophene useful as 5-lipoxygenase inhibitors
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BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
2-amino-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid derivatives
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The present invention relates to 2-amino-5-oxo-5 H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid derivatives of the formula (I): ##STR3## wherein A is ##STR4## (R, R.sup.1 and R.sup.2 are independently hydrogen or lower alkyl and m is 0 or 1, with the proviso that when m is 1, R.sup.1 is hydrogen)
Derivatives of 3-hydroxyazabenzo[b]thiophene useful as 5-lipoxygenase inhibitors
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BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
Heterocyclic coumarin derivatives
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This invention relates to certain novel 3-nitrocoumarin derivatives, to a method for their preparation, to pharmaceutical compositions comprising such compounds and to their use in the treatment of certain allergic conditions.
It is known that some types of cells are activated by certain
Aromatic amidocarboxylic acids and pharmaceutical compositions thereof
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BACKGROUND OF THE INVENTION
This invention relates to new aromatic amidocarboxylic acid derivatives. More particularly, this invention relates to cinnamoylaminophenylalkylcarboxylic acid derivatives and cinnamoylaminophenoxyalkylcarboxylic acid derivatives which exhibit a strong antiallergic effect
1-Benzoxepino[4,3-c]pyridines
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The present invention is concerned with 11-oxo-1-benzoxepino[4,3-c]pyridines of Formula I: ##STR2## wherein R.sub.1 and R.sub.2 may be hydrogen, lower alkyl, cyano, carboxamido, carboxy, ethoxycarbonyl or tetrazolyl and R.sub.3 may be hydrogen, lower alkyl, halogen, hydroxy or lower alkoxy.
In the
Modulation of substance P by compounds containing calcium sulfate and methods relating thereto
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TECHNICAL FIELD
The present invention relates generally to a method of modulating substance P by compounds containing calcium sulfate, particularly syngenite, gorgeyite and gypsum, and more specifically, to the synthesis of such compounds as well as their use to treat a variety of conditions
Pharmaceutical compositions and methods of treating allergic conditions utilizing 2-nitroindane-1,3-dione derivatives as the active agent
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This invention relates to pharmaceutical compositions which are useful in the inhibition of the effects of certain types of antigen-antibody reactions, and are therefore useful in the prophylaxis and treatment of diseases associated with allergic or immunological reactions, e.g. certain types of
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