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14 rezultati
Transdermal absorptive drug formulation
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a transdermal absorptive drug formulation containing 3-isobutyryl-2isopropylpyrazolo-[1,5-a ]pyridine ( hereinafter referred to as ibudilast according to its international nonproprietary name) which is an improving drug
.DELTA.9 Tetrahydrocannabinol (.DELTA.9 THC) solution metered dose inhaler
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DESCRIPTION
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention is generally related to the therapeutic use of .DELTA..sup.9 Tetrahydrocannabinol (.DELTA..sup.9 THC). In particular, the invention provides a metered dose inhaler (MDI) for the aerosol administration of .DELTA..sup.9
.DELTA.9 tetrahydrocannabinol (.DELTA.9 THC) solution metered dose inhalers and methods of use
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention is generally related to the therapeutic use of .DELTA..sup.9 Tetrahydrocannabinol (.DELTA..sup.9 THC). In particular, the invention provides a metered dose inhaler (MDI) for the aerosol administration of .DELTA..sup.9 THC to
Modulation of substance P by compounds containing calcium sulfate and methods relating thereto
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TECHNICAL FIELD
The present invention relates generally to a method of modulating substance P by compounds containing calcium sulfate, particularly syngenite, gorgeyite and gypsum, and more specifically, to the synthesis of such compounds as well as their use to treat a variety of conditions
Amines that inhibit a mammalian anandamide transporter, and methods of use thereof
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BACKGROUND OF THE INVENTION
Mammalian Endogenous Cannabinoid System
The various elements of the mammalian endogenous cannabinoid system (ECS) constitute a variety of pharmacological targets for the broad group of compounds generally termed as cannabinoids. Included among these elements are two types
Amines that inhibit a mammalian anandamide transporter, and methods of use thereof
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Prijavite se / prijavite se
BACKGROUND OF THE INVENTION
Mammalian Endogenous Cannabinoid System
The various elements of the mammalian endogenous cannabinoid system (ECS) constitute a variety of pharmacological targets for the broad group of compounds generally termed as cannabinoids. Included among these elements are two types
Amines that inhibit a mammalian anandamide transporter, and methods of use thereof
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Prijavite se / prijavite se
BACKGROUND OF THE INVENTION
Mammalian Endogenous Cannabinoid System
The various elements of the mammalian endogenous cannabinoid system (ECS) constitute a variety of pharmacological targets for the broad group of compounds generally termed as cannabinoids. Included among these elements are two types
Treatment of emesis with morpholine tachykinin receptor antagonists
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SUMMARY OF THE INVENTION
This invention is concerned with novel compounds represented by structural formula I: ##STR2## wherein R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.11, R.sup.12, R.sup.13, A, B, p, Y and Z are hereinafter defined.
The invention is also concerned with pharmaceutical
Treatment of migraine with morpholine tachykinin receptor antagonists
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SUMMARY OF THE INVENTION
This invention is concerned with novel compounds represented by structural formula I: ##STR2## wherein R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.11, R.sup.12, R.sup.13, A, B, p, Y and Z are hereinafter defined.
The invention is also concerned with pharmaceutical
Chromane substituted benzimidazole derivatives
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BACKGROUND OF THE INVENTION
This invention relates to chromane substituted benzimidazole derivatives. These compounds have selective acid pump inhibitory activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for
Chromane substituted benzimidazole derivatives as acid pump antagonists
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BACKGROUND OF THE INVENTION
This invention relates to chromane substituted benzimidazole derivatives. These compounds have selective acid pump inhibitory activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for
Benzimidazole derivatives as selective acid pump inhibitors
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BACKGROUND OF THE INVENTION
This invention relates to tricyclic compounds. These compounds have selective acid pump inhibitory activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the treatment of disease
Urea compounds and their use as enzyme inhibitors
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FIELD OF THE INVENTION
The present invention relates to compounds and their uses, and in particular to compounds and their therapeutic use in the treatment or prevention of conditions having an association with substrates, such as the neurotransmitter anandamide, which are broken down by the fatty
Urea compounds and their use as enzyme inhibitors
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FIELD OF THE INVENTION
The present invention relates to compounds and their uses, and in particular to compounds and their therapeutic use in the treatment or prevention of conditions having an association with substrates, such as the neurotransmitter anandamide, which are broken down by the fatty
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