chloroform/mučnina

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Systemic inflammatory response due to chloroform intoxication--an uncommon complication.

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Well-known adverse effects of chloroform are drowsiness, nausea, and liver damage. Two cases with an uncommon complication due to chloroform intoxication are presented. In the first case, a general physician, because of nausea and dyspnea, admitted a 34-year-old woman to hospital. She developed a

"Experimentation" with chloroform.

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A young patient presented with unconsciousness, cardiac arrhythmias, arterial hypotension, and mild intravascular hemolysis after intentional inhalation of chloroform. After the initial complications had resolved, nausea, loss of appetite, and mild transitory jaundice developed.

The Brompton mixture versus morphine solution given orally: effects on pain.

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The Brompton mixture is widely used as an effective method for controlling pain in cancer patients. In a double-blind crossover trial a standard Brompton mixture containing morphine, cocaine, ethyl alcohol, syrup BP and chloroform water was compared with morphine alone in a flavoured aqueous

Development and Evaluation of Naproxen Sodium Gel Using Piper cubeba for Enhanced Transdermal Drug Delivery and Therapeutic Facilitation.

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BACKGROUND The absorption of drug through skin avoids many side effects of oral route like gastric irritation, nausea, systemic toxicity etc and thus improves patient compliance. Naproxen sodium (NPRS) is one of the potent NSAID agents. OBJECTIVE The present study was aimed to develop and evaluate

Charles Darwin and the Dentists.

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Charles Darwin suffered relapsing, debilitating illness for most of his adult life with many symptoms. His most prominent complaints were episodic nausea, retching and vomiting. As is common in patients with repeated vomiting he developed dental problems, problems that may be dated back to his

An introduction to the clinical toxicology of volatile substances.

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Acute poisoning with organic solvents and other volatile compounds now usually follows deliberate inhalation (volatile substance abuse) or ingestion of these compounds. Solvents from adhesives, typewriter correction and dry cleaning fluids, cigarette lighter refills (butane) and aerosol propellants

Halothane Toxicity

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"Few drugs have excited such widespread interest and stimulated as much clinical and laboratory investigation as halothane." —Editorial, Brit. J. Anaesth. (1962).[1] Halothane is a clear, heavy, and colorless liquid with a sweet and non-irritating odor. Halothane’s structure is that of an

A RESEARCH UPON ANAESTHESIA.

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THE CONCLUSIONS WHICH HAVE BEEN REACHED BY THE SERIES OF EXPERIMENTS RECORDED IN THE PRESENT MEMOIR ARE: First. Lowered arterial pressure has a comparatively feeble effect upon the respiration, but when the pressure falls sufficiently, respiratory depression does occur. Second. Even excessive

Monitoring of DNA damage in individuals exposed to petroleum hydrocarbons in Ecuador.

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Currently, it is known that several chemical agents used or generated by the oil industry are classified as mutagens and/or carcinogens. Among these we have gasoline, diesel, butane gas, styrene, benzene, chloroform, and others. Studies have verified that these chemicals have effects in fertility

Clinical and pharmacokinetic study of oral etoposide in patients with AIDS-related Kaposi's sarcoma with no prior exposure to cytotoxic therapy.

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OBJECTIVE In this phase II and pharmacokinetic study, chronic, low-dose, oral etoposide was evaluated for its efficacy in patients with AIDS-related Kaposi's sarcoma who were not previously exposed to cytotoxic therapy. METHODS Of 28 patients accrued for the study, 25 were assessable for toxicity

Use of N-acetylcysteine in clinical toxicology.

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The major use of N-acetylcysteine in clinical toxicology is in the treatment of acetaminophen (paracetamol) overdosage. The hepatorenal toxicity of acetaminophen is mediated by a reactive metabolite normally detoxified by reduced glutathione. If glutathione is depleted, covalent binding to

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