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Iris pigmentation and extent of disease in patients with neovascular age-related macular degeneration.

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OBJECTIVE To determine whether the extent of disease in age-related macular degeneration (AMD) varies with iris pigmentation. METHODS The authors assessed visual function and macular appearance in the fellow eye or both eyes of 132 white patients with unilateral neovascular AMD. All patients had a

Urogenital atrophy: prevention and treatment.

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Fifteen percent of premenopausal women, 10-40% of postmenopausal women, and 10-25% of women receiving systemic hormone therapy experience urogenital atrophy. The most common symptoms are dryness, burning, pruritus, irritation, and dyspareunia. Estrogen loss, drugs, and chemical sensitivities are

Race, iris color, and age-related macular degeneration.

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OBJECTIVE While most observers agree that age-related macular degeneration (AMD) is much more common in white persons than in persons of black African ancestry, the influence of iris color has been more controversial. We reexamined relationships between race, iris color, and AMD in a series of

Cisplatin in children: hearing loss correlates with iris and skin pigmentation.

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Pigmentation is reported to affect cisplatin-induced ototoxicity in adult humans. The hearing loss is worse in people with brown irises, than in those with blue irises. We assessed the hypothesis that cisplatin-treated children with dark irises suffer more deterioration in auditory thresholds than

[Peculiarities of the clinical picture, diagnosis and prognosis of insulinoma].

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It is reported on a patient with insulinoma whose diagnosis was made 16 years ago. Operation report: Insulinoma with the histological picture of a little expressed malignant degeneration. After 6 years recidivation of the clinical picture of an insulinoma. Operation report: Metastasis of a malignant

Characterization of melanin in human iridal and choroidal melanocytes from eyes with various colored irides.

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Variance in iris color is related to the incidence of several important ocular diseases, including uveal melanoma and age-related macular degeneration. The purposes of this study were to determine the quantity and the types of melanin in cultured human uveal melanocytes in relation to the iris

Iris color and macular pigment optical density.

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The present study was designed to assess the relationship between iris color and macular pigment optical density. Both melanin and carotenoids (responsible for iris color and macular pigment composition, respectively) appear to protect the retina through similar mechanisms and higher concentrations

Associations between macular pigment, iris color and reflectance, ethnicity, and color vision: An observational study.

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Conflicting findings exist in the literature with regard to the relationship between iris color, ethnicity, macular pigment optical density (MPOD), and hue discrimination. This study re-examined these relationships, accounting for factors that may have confounded prior studies.

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