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encephalitis/gojaznost
Veza se sprema u međuspremnik
Page 1 od 21 rezultati
Antagonists of CB1 receptor
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The present application is filed pursuant to 35 U.S.C. 371 as a U.S. National Phase application of International Patent Application No. PCT/EP2012/059310, which was filed May 18, 2012, claiming the benefit of priority to European Patent Application No. 11305625.3, which was filed on May 20, 2011.
Antagonists of CB1 receptor
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FIELD OF THE INVENTION
The present invention relates to compounds for use in the treatment of a pathologic condition or disorder selected from the group consisting of bladder and gastrointestinal disorders; inflammatory diseases; cardiovascular diseases; nephropathies; glaucoma; spasticity; cancer;
Butanol extract of Bidens pilosa
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BACKGROUND
T cells, a class of lymphocytes developed in the thymus, are responsible for cell- and antibody-mediated immunity. Two major classes of T cells perform very different functions. CD8.sup.+ cytotoxic T cells kill infected cells or eliminated microorganisms, and CD4.sup.+ helper T cells help
Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Substituted naphthyridinone derivatives
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Substituted furo[2,3-b]pyridine derivatives
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Substituted pyrimidines
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Substituted 3-alkyl and 3-alkenyl azetidine derivatives
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis saliva L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Substituted 3-alkyl and 3-alkenyl azetidine derivatives
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Substituted 2,3-diphenyl pyridines
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Heterocycle-substituted 3-alkyl azetidine derivatives
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
CB1 antagonist compounds
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA..sup.9-tetrahydrocannabinol (.DELTA..sup.9-THC). Detailed research
Aralkyl amines as cannabinoid receptor modulators
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BACKGROUND OF THE INVENTION
Marijuana (Cannabis sativa L.) and its derivatives have been used for centuries for medicinal and recreational purposes. A major active ingredient in marijuana and hashish has been determined to be .DELTA.9-tetrahydrocannabinol (.DELTA.9-THC). Detailed research has
Substituted imidazoles as cannabinoid receptor modulators
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SUMMARY OF THE INVENTION
The present invention is concerned with substituted imidazole of the general Formula I:
##STR00001## and pharmaceutically acceptable salts thereof which are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention
Substituted imidazoles as cannabinoid receptor modulators
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SUMMARY OF THE INVENTION
The present invention is concerned with substituted imidazole of the general Formula I:
##STR00001## and pharmaceutically acceptable salts thereof which are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention
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