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12 rezultati
Steroid levels after intramuscular injection of radioactive estradiol-17beta, estrone, progesterone and testosterone in the bovine.
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Eight 2 year old Hereford cows from days 8 to 12 of the estrous cycle were injected intramuscularly with 5 ml of corn oil containing 5 mg of estradiol-17beta (two cows), estrone (two cows), progesterone (two cows) or testosterone (two cows). Each cow treated with estradiol received 494 microc of
Lack of tumorigenicity of cholesterol epoxides and estrone-3,4-quinone in the rat mammary gland.
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The purpose of this study is to test the long-standing hypothesis that endogenous agents found in human breast fluid and in plasma are potential initiators of breast cancer. Therefore, we evaluated the tumorigenicity in the mammary glands of female CD rats of cholestan-5 alpha,6 alpha-epoxy-3
Estrone is neuroprotective in rats after traumatic brain injury.
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In various animal and human studies, early administration of 17β-estradiol, a strong antioxidant, anti-inflammatory, and anti-apoptotic agent, significantly decreases the severity of injury in the brain associated with cell death. Estrone, the predominant estrogen in postmenopausal women, has been
Differential Regulation of Gonadotropins in Response to Continuous Infusion of Native Gonadotropin-Releasing Hormone in the Winter Anovulatory Mare and Effects of Treatment With Estradiol-17β.
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We tested the hypotheses that in winter anovulatory mares (1) both chronic daily injections of estradiol-17β (E2) and subcutaneous E2 implants could enhance pituitary secretion of gonadotropins in response to continuous subcutaneous infusion of native gonadotropin-releasing hormone (GnRH); and (2)
Effects of nonylphenol administration on serum, liver and testis estrogen metabolism.
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Secretory function of the ovine uterus: effects of gestation and steroid replacement therapy.
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In Exp. 1, changes in uterine fluid content of protein, calcium and prostaglandin F2 alpha (PGF) were examined between d 30 to 144 of gestation. Volume of uterine fluid (mean +/- SE) in the nongravid uterine horn of unilaterally pregnant ewes increased (P less than .05) between d 30 (8 +/- 1 ml) and
Serum estrogens and estrogen responsiveness in 7,12-dimethylbenz[a]anthracene-induced mammary tumors as influenced by dietary fat.
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The effect of dietary fat on mammary tumor incidence, estrogen-binding capacity as related to the hormone dependency of the tumors, and circulating estrogen levels in Sprague-Dawley rats given an oral dose of 7,12-dimethylbenz[a]anthracene (DMBA) was investigated. Rats were fed diets consisting of
Dietary fat in relation to hormonal induction of mammary and prostatic carcinoma in Nb rats.
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Mammary carcinoma was induced in female Nb rats by implanting pellets of estrone at 25-28 days of age, and prostatic cancer was induced in male rats of the same strain by repeatedly implanting pellets of testosterone propionate. Feeding semipurified diets containing either 3% or 20% corn oil did not
Estriol- and estradiol-17 beta-induced luteinizing hormone release in ovariectomized cows and ewes.
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Two studies were conducted with ovariectomized animals to compare luteinizing hormone (LH) responses during the 24-hr period following an IM injection of either estriol or estradiol-17 beta. In Exp. 1, six long-term ovariectomized (6 months) beef cows were randomly assigned to be given 1 mg of
Stimulating effects of 4-chlorodiphenyl ether on surgically induced endometriosis in the mouse.
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The objectives of this study were to evaluate the effects of repeated injection of 4-chlorodiphenyl ether (4-CDE) on the survival and growth of endometriotic implants. Endometriosis was surgically induced in adult female B6C3F1 mice (n = 25) after ovariectomy. Seven days later the animals were
A transcriptome approach evaluating effects of neonatal androgen and anti-androgen treatments on regulation of luteal function in sexually mature pigs.
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The current study was designed to gain insights into regulatory mechanisms mediating long-term effects of androgen excess or deficiency on corpus luteum function in pigs. Piglets were injected subcutaneously with testosterone propionate (TP, an androgen), flutamide (FLU, an anti-androgen) or corn
Effects of androstenedione on in utero development in rats.
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This study was conducted to characterize the effect of androstenedione on estrous cyclicity, mating behavior and fetal development. Thirty-day old rats received corn oil alone or androstenedione (in corn oil) at one of four concentrations (0, 1.0, 5.0, 10.0 or 30.0 mg/kg body weight) by gavage for
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