FIELD OF THE INVENTION
The present invention relates to the use of S-alkylisothiouronium derivatives, including, but not limited to, S-ethylisothiouronium diethylphosphate, for the prevention or treatment of headache, including but not limited to migraine, and for the prevention or treatment of
FIELD OF THE INVENTION
The present invention relates to the use of S-alkylisothiouronium derivatives, including, but not limited to, S-ethylisothiouronium diethylphosphate, for the prevention or treatment of headache, including but not limited to migraine, and for the prevention or treatment of
BACKGROUND ART
Magnesium (Mg) is the second most abundant cation in the body [Altura, B. M. et al., Drugs 28 (Suppl.I):120-142, 1984]. It is cofactor for more than 325 cellular enzymes involved in cellular energy production and storage, protein synthesis, DNA and RNA synthesis, cell growth and
BACKGROUND OF THE INVENTION
Migraine headaches affect approximately 9% (21 million female; 7 million male) of the population in the United States. The worldwide estimate of incidence is 650 million. There are a number of different forms of migraine. A principal characteristic of all migraines is
FIELD OF THE INVENTION
This invention relates to magnesium-based compositions for treating migraine headaches, and methods for using the same.
BACKGROUND OF THE INVENTION
Analgesic compositions comprising magnesium salts have been used to treat a variety of ailments as well as reduce the gastric
FIELD OF THE INVENTION
This invention relates to magnesium-based analgesic compositions for treating migraine headaches, and methods for using the same.
BACKGROUND OF THE INVENTION
Analgesic compositions comprising magnesium salts have been used to treat a variety of ailments as well as reduce the
This invention relates to a method of treatment of migraine, cluster headaches and trigeminal neuralgia, radiation or cytotoxic agent induced nausea and vomiting and/or cardiac arrhythmia in mammals, including humans, and to the use of compounds in the preparation of a medicament for the treatment
BACKGROUND OF THE INVENTION
1. Field of the Invention
The compounds of this invention are analogues of natural prostaglandins.
Natural prostaglandins are salicyclic compounds related to prostanoic acid, the structure of which is: ##STR2## By convention, the carbon atoms of I are numbered
FIELD OF THE INVENTION
The invention relates to methods of treating mammals, for example humans, to reduce the occurrence of undesired administration reactions, to treat an LFA-1 mediated disease, to condition a mammal to tolerate high doses of a therapeutic compound and to down modulate a cell
FIELD OF THE INVENTION
The invention relates to methods of treating mammals, for example humans, to reduce the occurrence of undesired administration reactions, to treat an LFA-1 mediated disease, to condition a mammal to tolerate high doses of a therapeutic compound and to down modulate a cell
FIELD OF THE INVENTION
The invention relates to methods of treating mammals, for example humans, to reduce the occurrence of undesired administration reactions, to treat an LFA-1 mediated disease, to condition a mammal to tolerate high doses of a therapeutic compound and to down modulate a cell
BACKGROUND OF THE INVENTION
The present invention provides a prodrug of propofol and crystalline forms thereof, methods of making the propofol prodrug and crystalline forms thereof, pharmaceutical compositions of the propofol prodrug and crystalline forms thereof, methods of using the propofol
BACKGROUND OF THE INVENTION
The present invention provides a prodrug of propofol and crystalline forms thereof, methods of making the propofol prodrug and crystalline forms thereof, pharmaceutical compositions of the propofol prodrug and crystalline forms thereof, methods of using the propofol
TECHNICAL FIELD
The present invention relates generally to a method of modulating substance P by compounds containing calcium sulfate, particularly syngenite, gorgeyite and gypsum, and more specifically, to the synthesis of such compounds as well as their use to treat a variety of conditions
BACKGROUND OF THE INVENTION
Although it is often said that the common cold is the most prevalent disease among humankind, it is also true that chronic pain is an affliction that is almost as prevalent. Chronic headaches, muscle pain, joint pain, and the like are experienced by most individuals, and
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