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Factors Influencing Postural Balance and Movement in Individuals With Stroke

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Background Postural control is an important component of movement. Prior to movement initiation, it is necessary to control posture such as gait initiation. Individuals with stroke often show impairment in both postural control and voluntary movement. The deficiencies restrict individuals with

L-Citrulline Dose Finding Safety Study in MELAS

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The human body is made of many cells and each cell contains many mitochondria. Mitochondria are called the powerhouses of the cell, because they produce the energy needed for a cell to be healthy and function the way it is meant to. Diseases of the mitochondria affect the way the tissues and cells

STRICTLy CFT: a Compassion Focussed Therapy Intervention to Aid Recovery Post-stroke

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Stroke Stroke is a type of acquired brain injury (ABI) and is a heterogeneous term used to describe both ruptures to large blood vessels in the brain causing flooding with blood, and occlusions of tiny vessels in a part of the brain that is vital for functioning. In the UK stroke is the second

BarcelonaBeta Dementia Prevention Research Clinic: a Study on Risk Factors Disclosure

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Effects of Magnesium Supplementation on Hemodynamic Parameters and Cognitive Function

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Dementia is an important geriatric syndrome. The prevalence of dementia increases with age. According to the data of the Taiwan Alzheimer Disease Association, one out of 13 elderly people over 65 and one out of 5 elderly over 80 had dementia. Almost 20% of the elderly people have the mild cognitive

Effects of Repetitive Hyperbaric Oxygen Therapy in Patients With Acute Ischaemic Stroke

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Study Methods: Study Population A 60 adult (aged >18 years) patients were included with a diagnosis of acute thromboembolic ischemic stroke within 48 hours after onset, according to clinical picture and imaging findings by brain computed tomography (CT) without evidence of hemorrhage, upon admission

Biomarker for Patients With Fabry Disease (BioFabry)

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Fabry disease is a progressive, inherited, multisystemic lysosomal storage disease characterized by specific neurological, cutaneous, renal, cardiovascular, cochleo-vestibular and cerebrovascular manifestations. Annual incidence is reported to be 1 in 80,000 live births but this figure may

Preoperative Cognitive Screening in Older Spinal Surgical Patients

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This project is designed as a prospective, single-center observational study. The cohort will consist of 500 consenting subjects ≥ 65 years of age who present to the Brigham and Women's Hospital Weiner Center for Preoperative Evaluation (CPE) prior to elective thoracic surgery (specifically,

Perinatal Stroke: Understanding Brain Reorganization

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Background and Significance Perinatal stroke affects more than1 in 2,300 live births. Perinatal stroke is the most common cause of hemiparetic cerebral palsy (CP). Even with prompt behavioral therapy, ongoing significant residual motor impairments are common in these children. In this case,

The Effects of Compensatory Auditory Stimulation and Transcranial Direct Current Stimulation on Tinnitus Perception

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Tinnitus refers to persistent "ringing in the ears" in absence of external sound. For some individuals tinnitus can be disabling. Most tinnitus is of idiopathic origin and currently there are no reliable treatment options available. Existing approaches, such as hearing aids, counseling, and noise

Improving Surgical Safety of Seniors Through Preoperative Cognitive Screening

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The overriding hypothesis is that structured preoperative cognitive screening of seniors is feasible without specialized staff and can help preoperatively identify persons at high risk of complications. To demonstrate generalizability of the single center experience, and strengthen the case for

Target Hemodynamics and Brain Injury During General Anesthesia in the Elderly

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BACKGROUND Post-operative cognitive dysfunction (POCD) is defined as a spectrum of postoperative central nervous system dysfunctions both acute and persistent, including subtle neurologic signs and neuropsychological impairment. The incidence of POCD is clearly associated with the age of patients,

A Study of Bezafibrate in Mitochondrial Myopathy

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Mitochondrial disorders are genetically determined metabolic diseases affecting approximately 1 in 5000 people. Current strategies for treating mitochondrial disorders are limited, and restricted to alleviating symptoms. A recently published Cochrane review did not identify any disease modifying

Therapeutic Efficacy of "Abroma Agusta" in HbA1c % in NIDDM

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Introduction: Diabetes mellitus type 2 (noninsulin-dependent diabetes mellitus (NIDDM) or adult-onset diabetes) is a metabolic disorder that is characterized by hyperglycemia (high blood sugar) in the context of insulin resistance and relative lack of insulin. According to recent survey reports

Lumbar Puncture and Syphilis Outcome

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