Group1 is control group and participants do not need intervention.

Group 2 is vinegar Group and participants in this group are asked to drink 15ml vinegar(Ninghuafu, Sanxi, China)after dinner at noon and evening respectively for a period of four weeks.

Urolithiasis

Each participant in vinegar group drink 15ml vinegar(Ninghuafu,Sanxi,China)after dinner at noon and evening respectively for a period of four weeks.

Vinegar group

Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University

Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Stone Formation

The Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Calcium Oxalate Urinary Stone Formation: a Randomised Controlled Trial

To compare the change of 24-hour urinary risk factors associated with calcium oxalate urinary stone formation which include Ph, volume, creatinine, oxalate, citrate, phosphate, uric acid, calcium, magnesium, sodium and chloride of 24-hour urine between two groups on the 7th,14th,21th and 28th day after drinking vinegar.

To compare the change of blood biochemical parameters which include fasting serum glucose, creatinine, urea, uric acid, high-density lipoprotein, low-density lipoprotein, triglycerides,serum total bile acid, cholesterol, sodium, potassium, calcium and chloride ions before grouping and on the 28th day after drinking vinegar.

To compare the change of blood oxidative stress markers which include blood protein product(AOPP),MDA,glutathion peroxidase(GSH-PX),superoxide dismutase(SOD) and catalase activity(CAT) before grouping and on the 28th day after drinking vinegar.

Guohua Zeng

Vice President of the Hospital

The First Affiliated Hospital of Guangzhou Medical University

Alport Syndrome

University Of Minnesota

Multi-center Controlled Clinical Trials in Alport Syndrome-A Feasibility Study

The primary outcome to be measured is the number of subjects with Alport syndrome who would meet eligibility criteria for an anticipated clinical treatment trial. Power calculations indicate that the trial would require recruitment of 90 total subjects, stratified into 4 groups based on urine albumin and protein excretion.

The primary outcome to be measured is the differences in urinary uromodulin excretion in Alport subjects stratified by urinary albumin excretion.

University of Minnesota

University of Utah

Peking University First Hospital

University of Toronto

University of Göttingen

Hôpital Necker-Enfants Malades

ACE I, ATA II and Statins

Patients will be given a low dose of Benazepril, 10 mg/die,that, if tolerated, will be up-titrated, after a week,to 20 mg/day.
Patients will be given Valsartan, 80 mg/die,up-titrated after a week to 160 mg/die. Fluvastatin will be started at 40 mg/die.If tolerated, will up-titrated to 80 mg/die. In case of liver, muscular or renal toxicity, fluvastatin will be back-titrated to 40 mg or withdrawn as deemed appropriate.

hematuria/albumin

Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Stone Formation

Multi-center Controlled Clinical Trials in Alport Syndrome-A Feasibility Study

Effects of an Intensified Treatment With ACE-I,ATA II and Statins in Alport Syndrome

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