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Chronic Myloid Leukemic Patients Treated With Tyrosine Kinase Inhibitor

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Chronic myelogenous leukemia (CML) is a myeloproliferative disorder in which leukemic cells display the Philadelphia chromosome generated from a reciprocal t(9:22) (q34:q11) translocation.1 The chromosome 9 and chromosome 22 transposal of t (9:22) and (q34:q11) causes the cancer gene C-ABL at 9q34

Assessment of the Different Etiological and Susceptibility Markers in Patients With Pancreatitis: Investigating IG4, Cytomegalovirus, Coxsackie- Virus, Genetic Polymorphism of Vitamin D Receptor Gene

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Acute pancreatitis is the most common pancreatic disorder. Although acute pancreatitis is a benign disease, it often progresses to a serious state, and mortality is still high. Autoimmune pancreatitis (AIP) was first used to describe cases of pancreatitis with narrowing of the pancreatic duct,

Diagnosis of Ascites in Infants and Children

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Definition : Ascites is the pathologic fluid accumulation within the peritoneal cavity . causes of ascites in infants and children : - Hepatobiliary disorders (cirrhosis, congenital hepatic fibrosis, acute hepatitis B,C ,Budd -chiari syndrome, Bile duct perforation) - Serositis (crohn's disease,

Biomarker for the Early Diagnosis and Monitoring in Tyrosinemia Type 1 (BioTyrosin)

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Hereditary Tyrosinemia type 1 (HT-1) is a rare genetic disorder in which the newborn child lacks the ability to break down the amino acid tyrosine. As a result of this deficiency, toxic sub-stances build up in the blood and can cause liver failure, kidney dysfunction and neurological problems. There

A Study of Impact of Anemia on Morbidity and Mortality in Children With Dilated Cardiomyopathy

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The clinical diagnosis of dilated cardiomyopathy is made from history, physical examination, and noninvasive testing. The initial clinical manifestations of dilated heart failure are generally those of respiratory distress secondary to congestion of the pulmonary and systemic venous

Radiation Dose Optimization in Diffuse Large B- Cell Lymphoma.

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Patients who fit the eligibility criteria will be screened for the trial. Patients who consent to participate in the trial will be registered into the trial prior to the start of chemotherapy. Patient registration / randomization procedure After completion of staging, the patient is informed about

Use of F-652 in Patients With Alcoholic Hepatitis

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IL-22 is a member of the IL-10 family of cytokines which control bacterial infection, homeostasis, and tissue repair. IL-22 may be used to treat patients with ALD because of its antioxidant, anti-apoptotic, anti-steatotic, anti-microbial, and proliferative effect that have been demonstrated in

The Clinical Epidemiology of Hospitalized Dengue Cases in Malaysia

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Dengue infection have resurged and disseminated globally since late 1970s after successful eradication programs of the dengue vector Aedes mosquitoes in Latin America in the 1940s. It has been identified as the fastest spreading mosquito-borne viral disease by World Health Organization (WHO), which

Study on Newborn Babies With a Yellow Skin Color (Neonatal Jaundice Study)

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PROCEDURES DURING PREGNANCY During the first antenatal care visit the mother will have a gestational dating ultrasound to determine the accurate gestational age. During all antenatal care visits information about the mother will be collected as part of standard obstetric care: - Ethnicity - Age -

Relationships Between the Use of Antimalarial Drugs in Pregnancy and Plasmodium Falciparum Resistance

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OBJECTIVES Overall objective: To improve the use of malaria chemoprophylaxis in pregnancy. Specific objectives: To investigate the effects of weekly CQ, intermittent presumptive treatment with CQ, and with SP on placental, peripheral, and cord parasitaemia and on P. falciparum resistance status in

Anti-Tac(Fv)-PE38 (LMB-2) to Treat Chronic Lymphocytic Leukemia

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Background: It is estimated that 30-50% of patients with CLL have tumors that express cluster of differentiation 25 (CD25) (Tac or IL2R). Normal resting T-cells are not sensitive to LMB-2 due to insufficient CD25 expression. LMB-2 is an anti-CD25 recombinant immunotoxin containing variable domains

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