Page 1 od 144 rezultati
BACKGROUND OF THE INVENTION
This invention relates to novel bis[bis (diphenylphosphino)hydrocarbon]-, bis[bis(diethylphosphino)hydrocarbon]-, bis[diphenylphosphino-diethylphosphino)hydrocarbon]gold(I), silver(I) or copper(I) complexes or tris[bis(diphenylphosphino)ethane]dicopper (I) derivatives
BACKGROUND OF THE INVENTION
This invention relates to novel .alpha.,.omega.-bis(disubstitutedphosphino)hydrocarbon compounds, digold(I), digold(III), disilver(I) or dicopper(I) complexes thereof, pharmaceutical compositions containing, as an active ingredient,
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Mar. 2, 2016 is named 701586-067982-US_SL.txt and is 8,192 bytes in size.
FIELD OF THE
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 20, 2013 is named 701586-067982-US_SL.txt and is 8,192 bytes in size.
FIELD OF THE
SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 20, 2013 is named 701586-067982-US_SL.txt and is 8,192 bytes in size.
FIELD OF THE
FIELD OF THE INVENTION
The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating various forms of cancer.
BACKGROUND OF THE INVENTION
Cancer is the second most common cause of death in the United States, exceeded only
FIELD OF THE INVENTION
The present invention relates to N-thiolated .beta.-lactam compounds, and analogs and derivatives thereof, which potently induce neoplastic cell apoptosis or inhibit neoplastic cell proliferation. Specifically, the invention relates to methods of treating conditions
FIELD OF THE INVENTION
The present invention relates to N-thiolated .beta.-lactam compounds, and analogs and derivatives thereof, which potently induce neoplastic cell apoptosis or inhibit neoplastic cell proliferation. Specifically, the invention relates to methods of treating conditions
BACKGROUND OF THE INVENTION
This invention relates to novel [bis(diphenylphosphino)alkyl]bis-gold[I] derivatives which have tumor cell growth-inhibiting activity, pharmaceutical compositions containing such novel derivatives, and a method for treating tumor cells sensitive to such derivatives by
FIELD OF THE INVENTION
The invention is directed to novel synthetic C-glycolipids, which are useful in treating cancer, infectious diseases and autoimmune diseases. Specifically, the invention is directed to novel synthetic analogs of .alpha.-C-galactosylceramides, which are potent mediators of
FIELD OF THE INVENTION
The invention is directed to novel synthetic C-glycolipids, which are useful in treating cancer, infectious diseases and autoimmune diseases. Specifically, the invention is directed to novel synthetic analogs of .alpha.-C-galactosylceramides, which are potent mediators of
FIELD OF THE INVENTION
The present invention relates to novel immunologic reagents and their use in assays for the detection of polycyclic aromatic hydrocarbon (PAH)-DNA adducts as well as heteropolycyclic aromatic hydrocarbon (HAH)-DNA adducts. These adducts are uniquely important biomarkers for
This application is related to U.S. provisional application Ser. No. 61/747,477 filed Dec. 31, 2012; Ser. No. 61/747,481 filed Dec. 31, 2012; Ser. No. 61/747,485 filed Dec. 31, 2012; Ser. No. 61/747,487 filed Dec. 31, 2012; Ser. No. 61/747,492 filed Dec. 31, 2012; Ser. No. 61/747,472 filed Dec. 31,
FIELD OF THE INVENTION
The present invention is concerned with novel 5'-deoxy-cytidine derivatives, pharmaceutical compositions, a kit thereof for assisting a delivery of 5-fluorouracil selectively to tumor tissues and process for manufacturing the novel 5'-deoxy-cytidine
TECHNICAL FIELD
This invention is a method of treating cancer, both carcinomas and sarcomas, and viral infections, in particular HIV through the administration of a pharmaceutical composition containing a benzimidazole derivative. The composition is also claimed.
BACKGROUND OF THE INVENTION
Cancers