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hypothyroidism/carbohydrate

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11 rezultati

The Changes of Body Composition, Glucolipid Metabolism and Bone Metabolism in Obese Children After Weight Loss

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Obese children have a higher incidence of vitamin D deficiency (VDD), which resulted from unhealthy life style such as less time outdoors, more sedentary time, imbalance of dietary intake. Adipose tissue is the storage position of vitamin D, and the storage formation include 25-OHD2 and 25-OHD3.

Evaluation of the Pattern of Thyroid Dysfunctions in Patients With Metabolic Syndrome

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The metabolic syndrome (MetS) is a clustering of multiple risk factors for atherosclerotic cardiovascular disease such as central obesity, impaired fasting glucose (IFG) or type 2 diabetes mellitus (T2DM), elevated triglyceride (TG), reduced high density lipoprotein cholesterol (HDL-C) and

Impact of Ketogenic Diet on Lipoproteins in Refractory Epilepsy

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Controlled clinical trial composed of children of adolescents aged 1 to 19 years with refractory epilepsy drug polytherapy (antiepileptic drugs). Children of both sexes are being included. The control group receive the diet classical ketogenic while the case group receive the ketogenic diet modified

The Peds Obesity Study

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Severely obese adolescents (13 to 17 year old males and post-menarcheal females between the ages of 12 and 17) will be recruited through the University of Florida Health Pediatric Weight Management Center. Therefore, all these patients would have undergone a multifaceted assessment that is part of

Randomized Trial Comparing Sitagliptin to Placebo in Closed Loop

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Rationale: Sitagliptin has been extensively studied in patients with type 2 Diabetes Mellitus (T2DM). Sitagliptin increases endogenous GLP-1 (Glucagon like peptide) by inhibiting the break down of an enzyme DPP-4 (Dipeptidyl Peptidase 4). GLP-1 in turn results in glucagon suppression.This mechanism

Resting Energy Expenditure in Patients on the Waiting List for Liver Transplantation

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This cross-sectional and descriptive study was carried out at the Alfa Institute of Gastroenterology, Hospital of Clinics, Universidade Federal of Minas Gerais (UFMG). The research protocol was approved by the UFMG Ethics Committee. Patients with indication for liver transplantation, aged over 20

Carbohydrate Metabolism Disorder Frequency in Hypertriglyceridemia Induced by Bexarotene of Cutaneous T Cell Lymphoma

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Primary cutaneous lymphomas are the second group of extra nodal lymphomas after gastrointestinal lymphomas. Bexarotene is licensed for the treatment of epidermotropic cutaneous T cell lymphoma .The most common side effect of bexarotene is hypertriglyceridemia (82%) associated with

Sitagliptin Dose Determination Study

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Rationale: Sitagliptin has been extensively studied in patients with type 2 diabetes mellitus, but there are no documented studies in the literature to establish a safe and efficacious dose in type 1 diabetes mellitus. Our previous experience with exenatide, which is a GLP-1 agonist and also with

Calorie Restriction Retards the Aging Process

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HYPOTHESIS: Calorie restriction delays the ageing process and thus telomere erosion, due to a reduction of oxidative stress, via expression modulation of uncoupling proteins and sirtuins. RETROSPECTIVE STUDY: Approximately 1000 adults aged 40 to 55 years, that had participated in nutritional

Skittles(TM) Effective for Treating Hypoglycemia in Children With Type 1 Diabetes

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An open labeled, randomized, cross-over design will be used. Each subject will treat 5 hypoglycemic events with glucose, 5 with sucrose and 5 with fructose. Subjects will be randomized into order of treatment. Primary Objective: 1. To determine if sucrose and fructose are equally effective as

Exenatide and Metformin Therapy in Overweight Women With PCOS

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Objectives: The objective of the present proposal is to compare the clinical, endocrine and metabolic effects of therapy with exenatide and metformin alone, to combination therapy in women with PCOS. This study will serve as a pilot investigation to open perspectives for future investigations
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