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7 rezultati
Indole derivatives useful as progesterone receptor modulators
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FIELD OF THE INVENTION
The present invention is directed to novel indole derivatives, the pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical usage of these
Indole derivatives useful as progesterone receptor modulators
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FIELD OF THE INVENTION
The present invention is directed to novel indole derivatives, the pharmaceutical compositions containing them and their use in the treatment or prevention of disorders and diseases mediated by agonists and antagonists of the progesterone receptor. The clinical usage of these
2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
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BACKGROUND OF THE INVENTION
The use of hormone replacement therapy for bone loss prevention in post-menopausal women is well precedented. The normal protocol calls for estrogen supplementation using such formulations containing estrone, estriol, ethynyl estradiol or conjugated estrogens isolated
Aminoalkyl substituted 5,6,7,8-Tetrahydro-9H-Pyridino [2,3-B]indole derivatives
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to aminoalkyl substituted 5,6,7,8-tetrahydro-9H-pyridino[2,3-b]indole and 5,6,7,8-tetrahydro-9H-pyrimidino[4,5-b]indole derivatives, pharmaceutical compositions containing such compounds and their use in treating
Aminoalkyl substituted 5,6,7,8-tetrahydro-9H-pyridino [2, 3-B] indole and 5,6,7,8-tetrahydro-9H-pyrimidino [4, 5-B] indole derivatives: CRF1 specific ligands
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to aminoalkyl substituted 5,6,7,8-tetrahydro-9H-pyridino[2,3-b]indole and 5,6,7,8-tetrahydro-9H-pyrimidino[4,5-b]indole derivatives, pharmaceutical compositions containing such compounds and their use in treating
Nonpeptide endothelin antagonists
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BACKGROUND OF THE INVENTION
The present invention relates to novel antagonists of endothelin useful as pharmaceutical agents, to methods for their production, to pharmaceutical compositions which include these compounds and a pharmaceutically acceptable carrier, and to pharmaceutical methods of
Cyclic octapeptides and pharmaceutical preparations thereof, as well as processes for their manufacture, and their use
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The invention relates to novel cyclopeptides of the somatostatin type and processes for their manufacture, and also to pharmaceutical preparations containing these compounds and the use of these compounds or preparations for therapeutic purposes.
The invention relates especially to cyclopeptides
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